:,,14,68();();();(,);(,);(,,);(,);(,);();();(,);(,);();(),,,,,,,,,,,,,,:710038,,,HBsAg10%,3000,60%81%,16%,,13%44%;,20%;,50%[13],1978,,,,,,,198320002000,,;;;;[4],:;;(),2,,(),40%,,,;,,(),1524,,,40%,,17.1mol/L10,,();(),():(1);(2);(3)HBsAg,()()(,/);(4)12004271JClinHepatol,February2004.Vol.7,No.1©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,HBsAg,,,(40%,10),3:(1):,,,10,40%30%,,;(2):(),30%20%;(3):(),20%,,1944Lucke,,,10,1946Lucke[5],,,,(ful2minanthepaticfailure),(acutehepaticfailure),(subacutehepaticfailure),(lateonsethepaticfailure),[68]:(1);(2);(3)Bernuau,;,;[9]1998,,,2000(AASLD)(Dallas,TX.),[10]2002ABC1,:(1);(2);(3),,1(HE)AB(bypass)C/(shunts)HEHE()(2)HE,2000,,,,1..1,:,1993.52..5,:,2001.113WuJC,ChenCL,HowMC,etal.MultipleviralinjectionasthemostcommoncauseoffulminantandsubfulminantviralhepatitisinanareaendemicforhepatitisB:applicationandlimitationofthePolymeraseChainreacting.Hepatology,1994,198364,.(20009).,2001,1956605LuckeB,MalloryT.Falminantformofepidemichepatitis.AmJPathol,1946,228679456OgradyJG,SchlmSW,WilliamsR.Acuteliverfailure:redefiningthesyndromes.Lancet,1993,3422737BernuanJ,RueffB,BenhamouJP.Fulminantandsubfuminantliverfaiure:definitionsandcauses.SeminLivDis,1986,6971068BernuanJ,BenhamouJP.Classifyingacuteliverfailure.Lancet,1993,3422532629,..,2000,85810FerenciP,LockwoodA,MullenK,etal.MembersoftheWork2ingParty.Hepatology,2002,35716721(:2003-12-08)(:)22004271JClinHepatol,February2004.Vol.7,No.1©1995-2005TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.