磺胺嘧啶钠的血浓度测定及药动学参数计算

给药量880mgIVt(min)t(h)C(ug/ml)LogC50.0833110.87312.04120.200097.64461.99150.250028.54061.46300.500032.78561.52500.833315.21341.18注：只需在表格中填入采血时间、血药浓度、给药量。　　如果采血时间点少，则删除多余的行。　　其它栏内容为自动生成。药代动力学参数CORREL(r)=-0.8649slope=-1.0688intercept=2.0366r2=0.7481Y=A+BX2.4615h-10.2815h108.8ug/ml8.0889L44.2ug/ml·h19.9106L/hAUC0→∞=C0/Kel=Cltol=Vd*Kel=一室模型血管内给药一级动力消除药代动力学Kel=slope*(-2.303)=T1/2=0.693/Kel=C0=Aantilog=Vd=D0/C0=y=-1.0688x+2.0366R²=0.74810.000.501.001.502.002.500.00000.50001.0000051015300.1671.28801.1540.4540.497光密度1.12100.98700.28700.3300y=9.872*X+0.020811.08739.76452.85413.2786血药浓度110.873197.644628.540632.7856体重kg2.2药物浓度mg/kg400给药量880一室模型血管内给药一级动力消除药代动力学1.000045min0.3190.15201.521315.2134