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郑法雷:100730[]R692.5[]A[]10019057(2005)11072903[]/;(chronicrenalfailure,CRF),CRF,CRF,,,,CRF,,CRF,,1.:,,;,,(LPD),()LPD,,;,KA,LPD,CRF,,;2.:CRFLPDLPD(EAA)(KA),;,CRFEAA,EAANEAA(),,;,,L,,,,,3.:,LPD,CRF,CRFZeller,(0.6~0.76g/kg,n=33)18~24,(Ccr)(0.33ml/min)(1.0g/kg,n=35,Ccr1.01ml/mim)Walser76CRF(GFR10ml/min,GFR15ml/min)(0.4g/kg),1(354)Pedrini,1413108CRF,(0.6g/kg)GFR;,33%;,46%4.:,()1,,CRF(),27292005112211JClinInternMed,November2005,Vo,l22,No.111(FAO)74737473()7473*76()75~777480858194:*21.,NO2.TGF,3.NFKBAP14.PAF5.6.,7.,,8.CRF,CRF(30%~60%),,,CRF,;,3,(ureanitrogenappearance,UNA,ureanitrogengeneration,UNG)(NormalizedProteinEquivalentofNitrogenAppearanceRate,nPNA)(Proteincatabolismrate,PCR),nPNA:nPNA(g/24h)=PNA=7.62UNA(g/d)+19.0(g/d)nPNA(g/24h)=0.272UNA(mmol/d)+19(g/d)nPNAPCR,PCR,,nPNAHD,nPNA,nPNA;,,,nPNA,:nPNAPCR,(Alb)40g/L,(PA)(TF)3::,,,,/;(BMI):(SubjectiveGlobalAssessment,SGA)(PhysicalComponentScale,PCS)(MentalComponentScale,MCS)DMS(DialysisMalnutritionScore)MIS(MalnutritionInflammationScore):(1);(2)(UNA),(nPNA),(PCR)(3)::KPBUNScrUA:CRP,1,A()(1),L-,IGF1(2)/DNAD():,X(DEXA),(NMR),(TC)IGFI,SCrBUN()nPNA0.8g/kg/day,:Alb40g/L,PA290mg/L,TF2000mg/L,PCR0.8g/kg,TC1500mg/LSCrBUN(),IGF1300g/L,(),,80%(IBW)CRF1./:CRF,,0.6~0.8g/kg,,CRF15~20mg/L(133~177umol/l),(900mg/d),()(KA)(0.1~0.2g/kg)2.:,(50%),,(),,CRFLPD3.:,,,[(PUFA)/(SFA)1.01.5],,PUFA/SFA17302005112211JClinInternMed,November2005,Vo,l22,No.11~2,PUFASFA1~24.L:(),CRF,,,500~1500mg/d,,400~800mg/d,500~700mg/d,,,,,B6(10~100mg/d)B12(500ug/d)(5~15mg/d),,,L,L,3g/(1.5g~5.0g/)CRF(L)5.:,,,,;(rHuEPO)D3,(rHuGH)(IGFI),(:20051010)(:)张子彦柳惠荣:312000,[]R573[]B[]10019057(2005)11073101[];(Hp)(MALT),90%MALTHpHpMALT,Hp,HpMALT,MALT,MALT15,1.:MALT15,7,8,19~65,(44.204.23)2,2,12.:Hp,HpMALT,155,3,5,27,3,2,246.67%12,1,2AnnArbor,E16,E25,E3415,Hp13,2,86.67%,1510,66.67%,MALTB,,,,,MALT,,,46.67%:(1),,;(2),,,,,,,,;(3),Hp86.67%,HpMALT,Hp,35%~100%15,10,66.67%,,,(:20050610)(:)7312005112211JClinInternMed,November2005,Vo,l22,No.11