中国敏感性皮肤诊治专家共识

“”6011607072013“”ＲIT130671．6500322．2002403．7100004．4000385．1001426．7100007．6100418．1100019．20004010．10003411．41000812．20044313．21004214．51063015．23003216．10002917．65003118．57000019．21000020．40003821．4300[e-mail]20171311Jan2017Vol．31No．1CHINJDEＲMVENEＲEOL001··12345678910111213141581191617181920212223242526121Ｒ593．1A1001－7089201701－0001－04DOI10.13735/j.cjdv.1001-7089.201611168sensitiveskinSS、、、、、、1。25.4%～89.9%50%。22.3%～50.9%40%～55.98%2-736.1%8-9。。、、《》。11.1、、、。1010-11。12。1.2①、、21013②、、、1013③。1.366%57%、、10。。2－－。。2.114-15。transepidermalwaterlossTEWL15-16。34℃42℃16。2.2、transientreceptorpotentialTＲP17－18。1transientreceptorpotentialvanilloid1TＲPV1TＲPV1、18。TＲPV1。19。2.3TＲPV1endothelinET。ET－1TNF－αIL－6VEGF1120。2.4TＲPV1P、、IL－23IL－31T17。33.1、、、、。3.2、、15-16。44.1、、。①、、②、、、A、、、③、2101321。4.2。4.2.110%50μL2.5min5min40123。≥314。4.2.2。0.8cm1cm0.1‰50μL12345。＞30S≥322。4.3。1162153pHpH4165236。5。5.1①、、、、·2·2017013101ChinJDermVenereolJan.2017Vol.31No.01②、、、、。5.2①、、②③≥3≥3④。6、、24－25。6.1。、、、、。25。6.2。、、。。。26。6.36.3.1、27。6.3.2。28。6.3.329。I、Ⅲ30。6.4、、、、。1．M．2010120－123．2InamadarACPalitA．SensitiveskinanoverviewJ．IndianJDermatolVenereolLeprol20137919－16．3MiseryLMyonEMartinNetal．SensitiveskinsinFranceanepidemiologicalapproachinFrenchJ．AnnDermatolVenereol20051325425429．4TaiebCAugesMGeorgescuVetal．SensitiveskininBrazilandＲussiaanepidemiologicalandcomparativeapproachJ．EurJDermatol2014243372－376．5MiseryLSibaudVMerial－KienyCetal．SensitiveskininAmericanpopulationprevalenceclinicaldataandroleofthedermatologistJ．IntJDer-matol2011508961－967．6VanoosthuyzeKZupkoskyPJBuckleyK．SurveyofpracticingdermatologistsontheprevalenceofsensitiveskininmenJ．IntJCosmetSci2013354388－393．7KamideＲMiseryLPerez－CullellNetal．SensitiveskinevaluationintheJapanesepopulationJ．Dermatol2013403177－181．8．J．2001407403－406．9．J．200830320－22．10BerardescaEFarageMMaibachH．SensitiveskinanoverviewJ．IndianJournalofDermatologyVenereology＆Leprology20133512－8．11MilsOHBergerＲS．DefiningthesusceptibilityofacneproneandsensitiveskinpopulationextrinsicfactorsJ．Demato1ogicclinics1991993－98．12DieamantGCPeredaMSamaraMDetal．NeuroimmunomodulatorycompoundforsensitiveskincareinvitroandclinicalassessmentJ．JournalofCosmeticDermatology200872112－119．13．J．201548167－69．14OhtaMHikimaＲOgawaT．PhysiologicalcharacteristicsofsensitiveskinclassifiedbystingingtestJ．JournalofJapaneseCosmeticScienceScoiety2000236163167．15ChoHJChungBYLeeHBetal．QuantitativestudyofstratumcorneumceramidescontentsinpatientswithsensitiveskinJ．JournalofDermatology2012393295－300．16PintoPＲosadoCParreiraoCetal．IsthereanybarrierimpairmentinsensitiveskinAquantitativeanalysisofsensitiveskinbymathematicalmodeling·3·2017013101ChinJDermVenereolJan.2017Vol.31No.01oftransepidermalwaterlossdesorptioncurvesJ．SkinＲesearchandTechnology2011172181－185．17DGLiHYDuSchmausGetal．InhibitionofTＲPV1preventedskinirritancyinducedbyphenoxyethanol．ApreliminaryinvitroandinvivostudyJ．Interna-tionalJournalofcosmeticscience201632101－6．18KawamataTJiWYamamotoJetal．Contributionoftransientreceptorpotentialvanilloidsubfamily1toendothelin－1－inducedthermalhyperalgesiaJ．Neuroscience200815431067－1076．19WeidnerCKledeMＲukwiedＲetal．AcuteeffectsofsubstancePandcalcitoningene－relatedpeptideinhumanskin－amicrodialysisstudyJ．Jour-nalofInvestigativeDermatology200011561015－1020．20ＲichtersＲFalconeDUzunbajakavaNetal．WhatissensitiveskinAsystematicliteraturereviewofobjectivemeasurementsJ．SkinPharmacolPhysi-ol201528275－83．21．J．20033211685－686．22．J．2014433190－193．23BerardescaEMaibachHI．SensitiveandethnicskinAneedforspecialskincareagents．J．DermatolClin19919189－92．24．BALB/cJ．2014475345－348．25．J．2015413141－142．26．862J．20158285－88．27MayoralFAKennerJＲDraelosZD．TheskinhealthandbeautypyramidaclinicallybasedguidetoselectingtopicalSkincareproductsJ．DrugsDerma-tol2014134414－421．28．J．20152916－8．29．J．201129112512－2514．30．LEDJ．20162879－81．31．104J．2009429607－609．32HeinickeIＲAdamsDHBarnesTMetal．EvaluationofatopicaltreatmentforthereliefofsensitiveskinJ．ClinCosmet＆InvestigationalDermatol20158405－412．2016-11-01《》2016“2016··”《》“”。《》7。“”《》。《》、、。《》。·4·2017013101ChinJDermVenereolJan.2017Vol.31No.01