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[InsertJournalEditor’snamehere]Editor-in-Chief[InsertJournalnamehere][Insertdatehere-DayMonthYear]DearDr[inserteditor’ssurnamehere],Wewouldliketosubmitourmanuscriptentitled“[inserttitleofyourmanuscripthere]”forpublicationasan[insertarticletypehere]in[insertjournalnamehere].[Providethebroadcontextofthework.Explaintheobjectiveofthestudyandhowthiswasnovel][Statethepossibleimportanceofthefindings.Explainhowthisisappropriateforthereadershipofthejournal]Weconfirmthatthismanuscripthasnotbeenpublishedelsewhereandisnotunderconsiderationbyanotherjournal.Allauthorshaveapprovedthemanuscriptandagreewithsubmissionto[insertjournalnamehere].Thestudywassupportedbyagrantfromthe[insertfundingbodyhere].Theauthorshavenoconflictsofinteresttodeclare.Pleaseaddressallcorrespondenceto:[Insertname][Insertcontactaddress,telephoneandfaxnumbers,ande-mailaddress]Welookforwardtohearingfromyouatyourearliestconvenience.Yourssincerely,[Insertname],[Inserttitle]

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