欢迎光临DxC800学习班学习班目标•帮助大家进一步了解仪器结构和特点•建立关于仪器的共同语言•对预防和解决一些常见故障有所帮助SynchronDxC800/600仪器概况DxC800/600内容提要•关于DxC800/DxC600•仪器特点•电路•水气路•常见故障及处理常用素语缩写•CAU:ChemistryAnalyticalUnit(仪器单元)•CC:CartridgeChemistries(formerRandomAccess-RA),CX4-side(试剂盒项目)•DMD:DualMotorDriver(步进电机)•Hydropnumaticsystem(水气路系统)•ICC:InstrumentControlComputer(仪器控制计算机)•ICS:InstrumentControlSubsystem(仪器控制系统)•MC:ModularChemistries(formerParallelProcess-PP),CX3-side(杯化学项目)•MPC:MultiProductConsole(控制台计算机)•MSMC:MultipleSmartModuleController(多智能模块控制器)•OS:OperatingSystem(计算机操作系统•PP:ParallelProcess,seeMC(并行处理)•RA:RandomAccess,seeCC(随机处理)•SM:SmartModule,forexampleDMD(智能模块)•TCP/IP:TransmissionControlProtocol/InternetProtocol(通信协议)DxC800/600概况•计算机(MPC)控制,外部采用网络连接.内部采用高速光纤连接.多任务,计算机分级管理.•随机处理(CC)与并行处理(MC)相结合的全自动生化分析仪器.•采用先进的智能化块(SM)化设计理念,互换性强,易于维修。•安全可靠的电源设计.•伺服电机使得控制调整更为方便.5个功能子系统MC部分(ModularChemistry)CC部分(CartridgeChemistry)样品装载部分控制台(MPC)其它-电源/水气/废液部分/仪器控制部分仪器硬件结构MC部分•杯化学项目(MC)“并行处理”处理急诊6个独立杯模块•流动池模块(ISE)--Na;K;Cl;Ca;CO2CC部分•DxC800/600CC部分分两层,可装载60个试剂盒•试剂盒项目(CC)“随机处理”每一试剂盒含3个试剂腔CCMCIinstrmentControlSystem&SmartModules(电路控制部分)•智能模块(SmartModule)•光纤互联•人性化设计,日常保养很少仪器设计特点仪器电路结构•InstrumentComputerSystem•ICS•MSMC•SmartModule仪器控制系统ICS•仪器控制中心(承上启下)•通过网线(以太网)与控制台计算机(MPC)连接.•通过2个MSMC(多智能模块控制器和光纤连接和控制12组智能模块回路(LOOP).仪器控制系统ICS智能模块(SmartModule)•机电自动控制基本单元.计算机单元(控制指令,通讯)马达控制单元功能单元(液面检测,温度控制…...)直流电压变换(5V,12V,15V……)•采用光纤互联各模块,环路(LOOP)方式.有效避免电气干扰,连接方便.•互换性好,更换方便.•信号传输速度快.SynchronLX-20ControlArchitectureOperatorInterfaceComputer(586)MPCInstrumentControlComputerDualPortRamMultipleSmartModuleController#1MultipleSmartModuleController#2DualPortRamDebugPortDebugPortPowerAlbuminModuleTPModuleCreatModuleGlucoseModulePhos.ModuleBUNModuleISEModulePPSampleSyringePPSampleCraneSamp.Wheel&LifterCapPierce&ShuttleTray&PusherHydroB.Jedruszczaklx20controlarchitecture-asize.dsfupdated:16-07-97LOOP2LOOP1LOOP4A1B1BulkReagentBarCodeReaderBC121116112131462635152LOOP3LOOP5LOOP631414243PhotometerAnalog940nmReaderFlashLampRxWheel&WashTimingfromEncoderonRxWheelTriggerPulseEncoderSignalsA2B2DebugPortSampleSyringeSampleCraneSampleMixerB1B2B3RxWheelHeaterRgtSwRegRefRotateReagentSyringeA1A2ReagMixerReagACraneReagBCraneC1C2C3LOOP8LOOP7LOOP9LOOP10LOOP12LOOP11917181FL182Note:940ReaderisasecondshipitemMCModulesMCSampleHYDROSampleRackCCReactionWheelPhotometerCCSampleDeliveryCCReagentDelivery13A14EthernetSampleBarCodeReaderRAReagentBarCodeReaderBC2BC31.DIP开关设置=模块号2.模块号第一位=环路号(LOOP)智能模块(SmartModual)PowerSubsystemDxC800电源•功能:提供+24.5VDC和+36VDC监控:-制冷驱动,ICS风扇速度监控-电源状态-试剂仓温度-24.5VDCand36VDC总线负载电流过载DxC800Power•DxC-3KVIsolatran-2PowerSupplies-One+24.5VDCOne+36.0VDC•1PowerDistributionBoardPowerSubsystemBlockDiagram220VACIN3KVISOLATRANCIRCUITBREAKER220VAC220VACTOPUMPBOXPUMPBOXRELAYSWITCH220VACTOPOWERSUPPLIES24.5&36VDCPOWERSUPPLIESPOWERDIST.BOARD24.5VDCBUSSES36VDCBUSSES24.5&36VDCICSPWR36/24.5VDCFANTACH'SINPUTFIBEROPTICSTOICSPELTIERSTATUS&TEMPERATUREPELTIERBUSSESSampleRackHandlingSubsystem样品输送系统(Autoloader)•样品传输主要部件自动进样器(pusher;gate;onload)管架进退传送器(gate;shuttle)退架装置(gate;offload;racklimitsensor)AutoloaderSubassemblySHUTTLEASSEMBLYescrewscrewscrewThreescrewsmustberemovedifyouwanttotaketheassyoff水气路部分CC部分•气压部分17PSI10PSI17PSI(排废)•水路部分DI浓缩清洗液去泡剂•真空/废液部分DxC水气路图MC部分CACLNAKNArefCOref2CO2ThermisterJ9J5J2BUFFERALKALINEEICDIWATERDRAINFLOWCELLREAGENTJJB0A010JINTERNALREFERENCECO2ACIDBUFFERFLOWCELLDRAINSOLUTIONGROUNDFLOWCELLGROUNDALKALINEPERI-PUMPDAMPERKILLERDRAINISEAIRBRAKEHYDROWASTE10HGVACUUMWASTE10HGELECTROLYTEINJECTIONCUPFLOWCELLJ8J62623252718243132332930282235BUFFERALKALINEINTERNALREFERENCECO2ACIDREAGENTBUFFERALKALINEBUFFERFLOWCELLDRAIN10HGVACUUMFORDRAINDIWATERISEFLOWDIAGRAM11121315DIWATERUTGUDEIEBGUIDETUBEMCModuleLED‘s•Green:MonitoredStatus-OK(BlinkingGreen–Temperatureoutofrange)•Red:CPUdead•Amber:IndicatestemperatureheatingandcoolingHYDROPNEUMATICMANIFOLD(CUPMODULES)DIWATERREGWASTEUNREGWASTE65A65T65C57T57A65G57B57G57C65P57PISE65BFLUIDDIAGRAM-CUPMODULESadoptedbyBJ,basedondrawing:466148-41rev.AAMicrografxDesigner6.0:Cupmodulesfluidflow.dsfCupModules,FluidflowDiagramDIWATERUNREG.WASTEREG.WASTEREAGENTLEGENDMCCups-ReagentFluidicsBUNmPHOSmGLUCmCREmTPmALBmM.C.MANIFOLD常见故障分析和排除常用工具仪器开机自检-MPC-ICS-MSMC-SmartModule仪器状态检查仪器诊断程序•常见故障Cuvettefailedwaterblanktest(杯空白测试失败)CC部分光路示意图Io光电检测器Electric1.2.3.信号处理电路冲洗站管路图及诊断方法吸走反应物加入清洗液吸走清洗液加入清洗液吸走清洗液加入去离子水吸走去离子水复位时水气路无响应(Hydrosub-systemnoresponse)贮水罐未在规定时间内充满(DIwaterreserviornofillatallintime)•观察贮水罐进水情况(大多数情况是外接水机压力不足)加试剂时检测到比色杯不干(Cuvettenotdrywhenprobeaddreagent)•可能原因比色杯未吸干试剂针高度调整有问题试剂针液面检测灵敏度废液排放故障主真空管路XXX运动错(XXXXmotionerror)•复位-确定出错部分查看状态屏幕查看故障记录观察相关智能模块上发光二极管状况电解质故障分析Na+K+Cl-CO2Na+Cl-K+ISEFlowcellClNaKRefBufferCO2ForNa/K/ClCO2RefForCO2AcidBufferin+-Ca成功定标三要素Range精度BacktoBack重复性Span灵敏度AnalogDigitalConversion浓度ADC***Cal1Cal2Back-To-BackCal1*B-BPassADCRangeCal2Cal1RangeSpan电解质定标示意图**定标报告•定标过程(样品周期+参比周期)•Sample-Reference•Sample•SampleDeviation•Reference•ReferenceDeviation常见故障讨论