猪血血红蛋白肽的研究进展

542011,Vol.25,No.06MEATRESEARCHCHINAMEATRESEARCHCENTER11122(1.1511002.301800)RecentAdvancesinResearchonPorcineHemoglobin-derivedPeptidesZHANGLi-juan1XIAJi-hua1SHENFeng1WANGYa-jing2CHENGYu-ming2(1.HeilongjiangBaodiMeatFoodCo.Ltd.,Zhaodong151100,China2.TianjinBaodiAgricultureandTechnology(Group)Co.Ltd.,Tianjin301800,China)AbstractInthispaper,porcinehemoglobin-derivedpeptidesaredescribedwithregardtotheirnutrientcomposition,processingtechnologies,structures,functions,andapplicationfieldsandprospects.Porcinehemoglobin-derivedpeptides,agroupofsmallbioactivepeptidesderivedfromporcineglobin,havesmallermolecularweight,highbioavailabilityandaddedvalue,agoodaminoacidbalanceandnutrition-enhancingeffectsandcanbedirectlyabsorbedwithoutdigestion.Porcinehemoglobin-derivedpep-tidescanalsopromotetheearlydevelopmentofthegastrointestinaltractandaminoacidabsorption,regulategastrointestinalmotilityandhaveimmunoenhancing,bloodpressureloweringandbloodlipidloweringandantioxidanteffects,thusbeingsuitableforuseinthefood,feed,dailychemicalandmedicinalfields.Keywordsporcinehemoglobin-derivedpeptidesnutrientcompositionmolecularstructurefunctionapplicationfieldsprospectTS251.93A1001-8123(2011)06-0054-042011-06-17(1983)[e-mail][1]l7l8(VB1VB2VB6VB12VD)(NaKCuZnCoCaPFe)[2][3-4](hemoglobinHb)80%[5][6][7][6][8][9][10]MEATRESEARCH552011,Vol.25,No.06CHINAMEATRESEARCHCENTER2pHpH()[12]3496%4%pH[13]2044.1[14][15]23(23)(1051)[16-20][21-24]4.2[25][25]4.3/(g/100g)/(g/100g)10.562.540.450.693.512.0311.575.758.007.553.120.764.267.190.256.778.222.452Table2Aminoacidcompositionofporcinehemoglobin-derivedpeptides/%/%84.02.060.00.10.58.00.21.01Table1Nutrientcompositionofporcinehemoglobin-derivedpeptides1(1)(2)95%Fe3+[11]562011,Vol.25,No.06MEATRESEARCHCHINAMEATRESEARCHCENTER[26]4.4[27][28]4.5(HDL)(TC)(TG)(LDL)TCTGLDL(angiotensin-convertingenzymeACE)ACEACE[29][30]ACE4.6[8][8][31][12]55.1[32][33-34][35]5.2VE[36]5.3X1)2)3)4)5)6)7)8)MEATRESEARCH572011,Vol.25,No.06CHINAMEATRESEARCHCENTER9)10)[37]6[1]BENJAKULS,VISESSANGUANW,SRIVILAIC.Porcineplasmaproteinasproteinaseinhibitorinbigeyesnappe(Priacanthustayenus)muscleandsurimi[J].JournaloftheScienceofFoodandAgriculture,2001,81:1039-1046.[2],,.[J].,2006,25(1):123-126.[3],,,.[J].,2009,26(8):61-63.[4],.[M].:,1997:85-86.[5],,,.CMS[J].,2007,25(3):41-43.[6],,,.[J].,2004,12(18):10-13.[7],,,.[J].,2010,24(3):31-35.[8].[D].:,2006.[9],,,.[J].,2008,31(2):64-65.[10],.[J].,2002,16(3):39-40.[11],,,.[J].,2007,33(1):10-15.[12],,,.[J].,2010,24(10):9-14.[13],,.[J].:,2007,16(1):19-22.[14],,,.[J].,2004(4):62-64.[15],,.[J].,2006,27(1):16-18.[16]CRAFTIL,GEDDESD,HYDECW,etal.Absorptionandmalabsorptionofglycineandglycinepeptidesinman[J].Gut,1968,9(4):425-437.[17]HARAH,FUNABIKIR,IWATAM,etal.Portalabsorptionofsmallpeptidesinratsunderunrestrainedconditions[J].JNutr,1984,114(6):1122-1129.[18]GANAPATHYV,LEIBACHFH.Peptidetransportinintestinalandrenalbrushbordermembranevesicles[J].LifeSci,1982,30(25):2137-2146.[19]CHENGB,NAVABF,LISMT,etal.Mechanismsofdipeptideuptakebyratsmallintestineinvitro[J].ClinSci,1971,40(3):247-259.[20]ADIBISA,FOGELMR,AGRAWALRM.Comparisonoffreeaminoacidanddipeptideabsorptioninthejejunumofspruepatients[J].Gastroenterology,1974,67(4):586-591.[21]LIUXQ,YONEKURAM,TSUTSUMIM,etal.Physico-chemicalpropertiesofaggregatesofglobinhydrolysates[J].JAgricFoodChem,1996,44:2957-2961.[22]LIUXQ,TSUTSUMIM.Gelformationofglobinpreparedbyacid-acetonemethodandglobinhydrolyzates[J].NipponShokuhinKogyoGakkaishi,1994,41(3):178-183.[23]MIYAGUCHIY,TSUTSUMIM,NAGAYAMAK.Gelationofporcinebypepsintreatment[J].FoodSciTechnolIntTokyo,1998,4(1):40-43.[24]MIYAGUCHIY,NAGAYAMAK,TSUTSUMIM.Gelationofporcinebloodglobinbycalfrennet[J].AnimSciTechnol,1996,67:482-483.[25].[D].:,2006.[26],.[J].,2000,14(2):11-13.[27]PANYX,WONGEA,BLOOMQUISTJR,etal.Expressionofaclonedovinegastrointestinalpeptidetransporter(oPepT1)inXenopusoocytesinducesuptakeofoligopeptideinvitro[J].JNutr,2001,131:1264-1270.[28].[J].,2008,33(1):16-18.[29],.()[J].,2002(4):9-10.[30],.ACE[J].,2009,23(2):21-24.[31].[D].:,2007.[32],,.[J].,2002,16(3):39-40.[33],.[J].,2001,4(6):5-8.[34],.[OL]..(2006-02-07)[2011-06-03].[35].[OL]..(2007-09-12)[2011-06-03].=081B0747065A4529925471B0F505F982fruitNo=3391.[36],,.[J].,2011,34(1):30-34.[37][OL].-.(2002-08-20)[2011-06-03].