海马结构的细胞构筑

整理文档很辛苦,赏杯茶钱您下走!

免费阅读已结束,点击下载阅读编辑剩下 ...

阅读已结束,您可以下载文档离线阅读编辑

资源描述

[2]GageFH.Mammalianneuralstemcells[J].Science,2000,287(5457):143321438.[3]SvendsenCN,SmithAG.Newprospectsforhumanstem2celltherapyinthenervoussystem[J].TrendsNeurosci,1999,22(8):3572364.[4]Martinez2SerranoA,BjorklundA.ImmortalizedneuralprogenitorcellsforCNSgenetransferandrepair[J].TrendsNeurosci,1997,20(11):5302538.[5]LiuY,HimesBT,SolowskaJ,etal.Inraspinaldeliveryofneurotrophin23usingneuralstemcellsgeneticallymodifiedbyrecombinantretrovirus[J].ExpNeurol,1999,158(1):9226.[6]LindvallO,BrundinP,WinderH,etal.Graftsoffetaldopamineneu2ronssurviveandimprovemotorfunctioninParkinsonsDisease[J].Science,1990,247(4942):5742577.[7]WoodburyD,SchwarzEJ,ProckopDJ,etal.Adultratandhumanbonemarrowstromalcellsdifferentiateintoneurons[J].JNeurosciRes,2000,61(4):3642370.[8]Sanchez2RamosJ,SongS,Cardozo2PelaezF,etal.Adultbonemarrowstromalcellsdifferentiateintoneuralcellsinvitro[J].ExpNeurol,2000,164(2):2472256.[9]AziziSA,StokesD,AugelliBJ,etal.Engraftmentandmigrationofhu2manbonemarrowstromalcellsimplantedinthebrainsofalbinorats22similaritiestoastrocytegrafts[J].ProcNatlAcadSciUSA,1998,95(7):390823913.[10]KopenGC,ProckopDJ,PhinneyDG.Marrowstromalcellsmigratethroughoutforebrainandcerebellum,andtheydifferentiateintoastro2cytesafterinjectionintoneonatalmousebrains[J].ProcNatlAcadSciUSA,1999,96(19):10711210716.[11]SunY,Nadai2VicensM,MisonoS,etal.Neurogeninpromotesneuro2genesisandinhibitsglialdifferentiationbyindependentmechanisms[J].Cell,2001,104(3):3652376.[12]JoheKK,HazelTG,MullerT,etal.Singlefactorsdirectthedifferenti2ationofstemcellsfromthefetalandadultcentralnervoussystem[J].GenesDev,1996,10(24):312923140.[13]GhoshA,GreenbergME.DistinctrolesforbFGFandNT23intheregu2lationofcorticalneurogenesis[J].Neuron,1995,15(1):892103.[14]BonniA,SunY,Nadal2VicensM,etal.RegulationofgliogenesisinthecentralnervoussystembytheJAK2STATsignalingpathway[J].Sci2ence,1997,278(5337):4772483.[15]WilliamsBP,ParkJK,AlbertaJA,etal.APDGF2regulatedimmediateearlygeneresponseinitiatesneuronaldifferentiationinventricularzoneprogenitorcells[J].Neuron,1997,18(4):5532562.[16]TakahashiJ,PalmerTD,GageFH.Retinoicacidandneurotrophinscol2laboratetoregulateneurogenesisinadult2derivedneuralstemcellcul2tures[J].JNeurobiol,1999,38(1):65281.[17]DoetschF,Garcia2VerdugoJM,Alvarez2BuyllaA.Cellularcompositionandthree2dimensionalorganizationofthesubventriculargerminalzoneintheadultmammalianbrain[J].JNeurosci,1997,17(13):504625061.[18]BrewerGJ.Regenerationandproliferationofembryonicandadultrathippocampalneuronsinculture[J].ExpNeurol,1999,159(1):2372247.:2003201211:20032092041,2(1.,111000;2.,116027):(2001102082):;;;;;:R322.8;R338.26:A:100622084(2003)1120683204(hippocampalformation)[124],:(hippoacampus)(dentategyrus)(subiculum),,1Ammons,,C,,S,(al2vens),,,,2,[128],,,,,12%:,GABA,,,,,,,,5,(stratummoleculare)(stra2tumlacunosum)(stratumradiatum)(stratumpyra2midale)(stratumoriens),6,,,,,,CA1CA2CA3CA4CA4,CA1,,,,,CA3,CA4,UV,()CA4,3862003911MedicalRecapitulate2003,Vol.9,No.11,(),,,,:33.1,(perforantpaths,PP),,,,,CA1CA1CA3CA4;,,[2,5]3.2,,,[2,5],,,,,,,(),,,,,,,,[6]:(mossyfiber,MF)CA3CA3SchafferCA1,CA1,PapezPapez(1937),:,,,,,,Papez,,,Nauta,:44.1,,CA3[7],,,,Ca(calbindin28KCABp2D228K),,Timms,[9]:14,,3221m,2324m4258m,,325m,176m,,48,2240,63%1P3,,30%1P3,30%1P3,40%1P3,,1P3,,(),1P3,4.2CA12CA4[8]CA3,[7],(chandeliercell)[1],:150060[10],2(GABA)(SS)Y(NPY)[6],2Jonansen[1],,55.1(Ach),[2,4,6]4862003911MedicalRecapitulate2003,Vol.9,No.11,AchAchT,Ach,5.2(Glu)(Asp)[2,4,6]GluAsp,GluAsp,GluAsp,AspCA3GluAspCA3GluAsp,Glu()Glu5.3[2,4,5],(dynorphin,DYN)DYN,,DYN5.4[2]5.4.1(CA)(NA)CA3CA1NA();(DA)()CA,CA1%,,,NA5.4.252HT52HT,52HT,52HT52HT,52HT5.4.3,,(HDC)95%HDC5.5[15],CA4CA1;CA1CA3,,6,[2,5,11,13,14]:,,,,;,,,,,,(),,,,,[17],,,[18],,[19];;,,,,,,,,;,,,,,:CA3CA12(kainicacid,KA),,,,[1,10]Alzheimer(AD)[12,16],AD,AchE,,,,CA3,,1P3,,,AD,ADAD,AD,AD,,,,CA3,:[1],,.[J].,1997,3(2):1032108.[2].[J].,1996,12(2):1772184.[3],,.[M].:,198612632285.[4].[M].:,198714822486.[5],.[M].1.:5862003911MedicalRecapitulate2003,Vol.9,No.11,199811622176.[6],.[M]1:,1992.1822189.[7]AlkonDL,AmaralDG,BearMF,etal.Learningandmemory[J].BrainResReviews,1991,16(2):1932220.[8],.[M].:,199514252455.[9]DesmondNL,LevyWB.Aquantitativeanatomicalstudyofthegranulecelldendriticfieldoftheratdentategyrususingnovelprobabilisticmethod[J].JCompNeurol,1982,237(3):2362245.[10]CalaiborneBJ,AmardDG,CowanWM.Quantitative,three2dimensionalanalysisofgranulecelldendritesintheratdentategyrus[J].JCompNeurol,1990,302(3):206.[11]RibarCE,NitschR,SeressL.Projectionofparalbumin2positivebasketCellintheGABAergicinnervationofpyramidalandgranulecellsoftherathippocampalformation[J].JCompNeurol,1990,330(5):4492461.[12],,,1[J].,1996,19(3):2082211.[13]AmaralDG.AGolgistudyofcelltypesinthehilarregionofthehipp2ocampusintherat[J].JCompNeurol,1978,182(8):851.[14]HarrisKM,JensenFE,TsaoB.Three2dimensionalstructureofdendriticspinesandsynapsesintherathippocampus(CA1)atpostnatalday15andadultages:Implicationsforthematurationofsynapticphysiologyandlong2termpotentiation[J].JNeurosci,1992,12(12):2685.[15],.[A].,.[M].:,199

1 / 4
下载文档,编辑使用

©2015-2020 m.777doc.com 三七文档.

备案号:鲁ICP备2024069028号-1 客服联系 QQ:2149211541

×
保存成功