内科学第8版风湿免疫疾病部分:美国风湿病学会(ACR)欧洲抗风湿联盟(EULAR)欧洲脊柱关节病研究组(ESSG)风湿性疾病rheumaticdisease结缔组织病connectivetissuediseases,CTD未分化的结缔组织病(undifferentiatedconnectivetissuediseases,UCTD)混合型结缔组织病(mixedconnectivetissuedisease,MCTD)骨关节炎osteoarthritis,OA韦格纳肉芽肿→肉芽肿性多血管炎granulomatosiswithpolyangiitis,GPAChurg-Strauss综合征更名为:嗜酸性肉芽肿性多血管炎(Eosinophilicgranulomatosiswithpolyangiitis,EGPA)肉芽肿性多血管炎(GPA)系统性红斑狼疮systemiclupusoferyematosus,SLE亚急性皮肤型红斑狼疮(SCLE)强直性脊柱炎Ankylosingspondylitis,AS类风湿关节炎rheumatoidarthritis,RA纽扣花样(boutonniere)天鹅颈(swanneck)皮肌炎dermatomyositis,DM多发性肌炎polymyositis,PM原发性干燥综合征,pSS系统性硬化症SSc大动脉炎TA贝赫切特病BDPIP(proximalinterphalangealjoint)近端指间关节DIP(distalinterphalangealjoint)远端指间关节MCP(metacarpophalangealjoints)掌指关节弥漫性肺泡出血(diffusealveolarhemorrhage,DAH)抗磷脂抗体综合征(antiphospholipidantibodysyndrome,APS)神经精神狼疮(neuropsychiatriclupus,NP-SLE)脊柱关节炎(Spondyloarthritis,SpA)血清阴性脊柱关节病(seronegativespondyloarthopathy)/脊柱关节病(spondyloarthropathies)包括:强直性脊柱炎AS(AnkylosingSpondylitis)反应性关节炎(reactivearthritis,ReA)银屑病关节炎(Psoriaticarthritis,PsA)炎性肠病关节炎(IBDA;inflammatoryboweldiseasearthritis)幼年脊柱关节炎(juvenile-onsetspondyloarthritis)未分化脊柱关节炎(Undifferentiatedspondylarthritis,USpA)原发性干燥综合征(primarySjogren'ssyndrome,pSS)血管炎(vasculitides)结节性多动脉炎(polyarteritisnodosa,PAN)肉芽肿性多血管炎granulomatosiswithpolyangiitis,GPA/韦格纳肉芽肿(Wegener'sgranulomatosis,WG)大动脉炎(takayasuarteritis,TA)巨细胞动脉炎(Giantcellarteritis,GCA)显微镜下多血管炎(microscopicpolyangiitis,MPA)风湿性多肌痛(polymyalgiarheumatica,PMA)贝赫切特病(Behcet'sdisease,BD)特发性炎症性肌病(idiopathicinflammatorymyopathy,IIM)皮肌炎dermatomyositis,DM多发性肌炎polymyositis,PM包涵体肌炎(inclusionbodymyositis,IBM)系统性硬化症(systemicsclerosis,SSc)又称硬皮病(scleroderma)CREST综合征:钙质沉着(Calcinosis,C)、雷诺现象(Raynaud'ssyndrome,R)、食道运动功能障碍(Esophagealdysmotility,E)、指端硬化(Sclerodactyly,S)、毛细血管扩张(Telangiectasis,T)POEMS综合征:是一种与浆细胞病有关的多系统病变,临床上以多发性周围神经病(polyneuropathy)、脏器肿大(organomegaly)、内分泌障碍(endocrinopathy)、M蛋白(monoclonalprotein)血症和皮肤病变(skinchanges)为特征,取各种病变术语英文字首组合命名为POEMS综合征。硬皮病肾危象renalcrisis弥漫皮肤型SSc(diffusecutaneoussystemicsclerosis)局限皮肤型SSc(limitedcutaneoussystemicsclerosis)无硬化病的SSc(systemicsclerosissinescleroderma)硬皮病重叠综合征(sclerodermaoverlapsyndrome)雷诺现象Raynaud'sphenomenon雷诺病Raynauddisease骨关节炎Osteoarthritis,OA骨赘osteophyte关节胶化articulargellingHeberden结节(位于远端指间关节)Bouchard结节(位于近端指间关节)弥漫性特发性骨肥厚diffuseidiopathicskeletalhyperostosis,DISH透明质酸hyaluronicacid痛风gout单钠尿酸盐(monosodiumurate)痛风石(tophi)白三烯B4(LTB4)白介素1(IL-1)骨质疏松症(Osteoporosis,OP)骨量(bonemass)骨密度(BMD)护骨素(osteoprotegerin,OPG)绝经后骨质疏松症(postmenopauseosteoporosis,PMOP)PTH相关蛋白(PTHrP)血抗酒石酸酸性磷酸酶(TRAP)戈谢(Gaucher)病反射性交感性营养不良症(reflexsympatheticdystrophy)纤维肌痛综合征(FibromyaigiaSyndrome,FMS)功能性磁共振脑成像(fMRI)自身抗体:抗核抗体(anti-nuclearantibodies,ANAs)可溶性抗原(extractablenuclearantigen,ENA)抗体类风湿因子rheumatoidfactor(RF)抗角蛋白抗体(anti-keratinantibodies,AKA)谱:抗核周因子(antiperinuclearfactor,APF)抗体抗角蛋白AKA抗环瓜氨酸肽(anti-cycliccitrullinatedpeptide,CCP)抗体抗磷脂抗体(antiphospholipidantibodies,APL)抗β2糖蛋白1(β2GP1)抗着丝点抗体(anti-centromereantibody,ACA)抗中性粒细胞胞质抗体(Anti-neutrophilcytoplasmicantibodies,ANCA)丝氨酸蛋白酶3(PR3)髓过氧化物酶(MPO)抗内皮细胞抗体(AECA)肌炎特异性抗体(myositisspecificantibody,MSA)药物:非甾体抗炎药(Non-steroidalanti-inflammatorydrug,NSAIDs)改善病情抗风湿药(diseasemodifyinganti-rheumaticdrugs,DMARDs)糖皮质激素(Glucocorticoid,GC)免疫球蛋白(IVIG)强的松(Prednisone)甲强龙(methylprednisolone)柳氮磺吡啶(salazosulfapyridine,SASP)硫唑嘌呤(azathioprine,AZA)甲氨蝶呤(Methotrexate,MTX)他克莫司(Tacrolimus)羟氯喹(Hydroxychloroquine,HCQ)环磷酰胺(Cyclophosphamide,CTX)环孢素A(cyclosporinA,CsA)雷公藤总苷(TripterygiumGlycosides,TII)吗替麦考酚酯(MycophenolateMofetil,MMF)来氟米特(Leflunomide,LEF)沙利度胺thalidomide依托考昔(Etoricoxib)秋水仙碱(Colchicine)异黄酮(isoflavone)塞来昔布(celecoxib)选择性雌激素受体调节剂Selectiveestrinreceptormodulator(SERM)选择性雄激素受体调节剂selectiveandrogenreceptormodulators(SARM)依替膦酸二钠(Etidronate)帕米磷酸钠(Pamidronate)阿仑膦酸钠(Alendronate)鲑鱼降钙素(Miacalcic)鳗鱼降钙素(Elcitonin)三环类抗抑郁药(TcAs)阿米替林(Amitriptyline)普瑞巴林(pregabalin)5-HT再摄取抑制剂(ssRJs)单胺氧化酶抑制剂(MAOIs)