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:1003-8701(2002)01-0050-04,,(,130062)::,,:;;;:S85216:A1(Microecologics)(Microbialgrowthpromoters)(Direct-fedmicrobials,DFM)20,10,,,,,,,,,,21989,(FDA)(AAFCO)411994:,,211,,,,,4001014,:2001-07-23:(1971-),(),,,2002,27(1):50-53JournalofJilinAgriculturalSciences©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,:10,100,,,,,,,,,:21111,(Competitiveexclusion),(Colonizationresistance),,,,,Ofek,,Oyofo,,,21112,,,pH,Gibson,,(Lactobacillusreuteri)reuterin,1530g/mL;60150g/mL,reuterin,Reuterin,3-(3-HPA)reuterin21113,,,21114,,,,,,,212151:©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,IL-1IL-6,SekineIL-1IL-6mRNA012%(),SOD35%SOD,IgG,,T(ANAE):,213,,,03,-,,,,,,,:Edens,214,,,,,Scheuermann(1993),Paciflor(,)NH3EM,NH3NH3NH3,,,NH3,3,,,,2527©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.,,,,,,,,,,,,,,,:[1]FullerR1Areviewprobioticsinmanandanimal1J1appl1Bact11989,66:265-3781[2]JonesFT1Useofdirect-fedmicrobialsnotnew;waytheyworkstillnotclear1Feedstuff1January28,1991131-341[3],1[M]1:,19941248-2541[4],1[M]1:,19941239-2471[5]SogaardH,etal1Microbialsforfeedbeyondlacticacidbacteria1FeedInternational11990,11(4):32-281[6]1[J]1,1999,11(1):15-181[7]SissonsJW1Potentialofprobioticorganismstopreventdiarrhoeaandpromotedigestioninfarmanimals-Areview1J1Sci1Food1Agric11989,49:1-131[8],1[J]1,1997,(3):15-171[9]StavricS&KornegayET1Microbialprobioticsforpigsandpultry1InBiotechnologyinAnimalFeedsandAnimalfeeding(Wallace,R1J1andChesson,A1ed1)Weinheim1NewYork11995,205-2311[10]HentyesDJ1Gutfloraindiseaseresistance1InProbiotics1TheScientificBasis(R1Fuller,ed)1ChapmanandHall,London,UK.19921[11]BarrowPA,etal1Theattachmentofbacteriatothegastricepitheliumofthepiganditsimportanceinthemicroecologyoftheintes2tine1JournalofAppliedBacteriology11980,48:147-1541[12]PedersenK,etal1Colonizationoftheporcinegastrointestinaltractbylactobacili1Appl1Environ1Microbiol11989,55(2):279-2831[13]StavricS,etal1RoleofadheringmicrofloraincompetitiveexclusionofSalmonellafromyoungchicks1JournalofFoodProtec2tion11987,50(11):928-9321[14]OfekI,etal1Surfacesugarsofanimalcellsasadeterminantofrecognitioninbacterialadherence1TrendsBiochem1Sci11978,31[15]OyofoBA,etal1EffectofcarbohydratesonSalmonellatyphimuriumcolonizationinbroilerchichens1AvianDis11989,331[16]GibsonGRandWangX1Regulatoryeffectsofbifidobacteriaonthegrowthofothercolonicbacteria1JournalofAppliedBacteriolo2gy11994,77:412-4201[17]ChungTC,etal.InvitrostudiesonreuterinbyLactobacillusreuteri1Microb1Ecol1Hith1Dis11989,2:137-1441[18]TalaricoTL,etal1PurificationandcharacterizationofglycroldehydratasefromLactobacillusreuteri1Appl1Environ1Microbiol11990,56:1195-11971[19]EdensFW,etal1PrinciplesofexovocompetitiveexclusionandinovoadministrationofLactobacillusreuteri1PoultryScience11997,76(1):179-1961[20]RolfeRD1Populationdynamicsoftheintestinaltract1Incolonizationcontrolofhumanbacterialenteropathogensinpoultry(Blankenship,L1C1,ed)1Academicpress,Inc1SanDiego,CA11991:59-751[21],,1[J]1,1996,8(4):34-381[22],,1IL-1IL-6[J].,1998,10(3).[23]SekineK,etal1Analysisofantitumorpropertiesofeffectorcellsstimulatedwithacellwallpreparation(WPG)ofBifidobacteriumin2fants1Biol1Pham1Bull11995,(18):148-1531[24],,1[J]1,1998,10(1):45-461351:©1995-2006TsinghuaTongfangOpticalDiscCo.,Ltd.Allrightsreserved.