正确使用环氧乙烷灭菌效果的监测方法

张晓春,许乐(,350001):,,3,:;;:R187+.2:A:1005-4529(2003)04-0346-02MonitoringofEthyleneOxideSterilizationZHANGXiao-chun,XULe(UnionHospital,FujianMedicalUniversity,Fuzhou350001,China)Abstract:OBJECTIVEToexploretheeffectivemonitoringmeasuresofethyleneoxide(EO)sterilization.METHODSTomonitorsterilizationeffectcomprehensively,adoptbiologicalindicator,andchemicalindicatortocontroldifferentpa-rameterandmechanicalstatusduringthesterilization.RESULTSThesterilizationqualitycanbeadvancedthroughfulfillrelatedstandardsandcriteriaintegratedwithphysical,chemicalandbiologicalmonitoringmeasures.CONCLUSIONSItisakeypointofsuccessfulsterilizationthatexactapplicationsofmonitoringmeasuresandrestrictqualitycontrol.Keywords:Ethyleneoxide;Sterilization;Monitoring,,,1,[1]:,,;,,,,,,:2002-11-26;:2003-01-2022.1生物指示剂监测,17,(biologicalindicator)21,ATCC9372,19912.2生物指示剂规定标准,,,(AAMI):(60030)mg/L,(542),(RH)60%10%,(CFU/)5105~5106,346ChinJNosocomiolVol.13No.42003ATCC9372,7.8min,58min,D2.6~5.8min[2]2.3监测方法AAMI:20ml,,,;;25.4cm(48.5mm,15.9mm),4(46cm76cm,100%),3,,6,4,;,,,,,3748h2.4监测频率AAMI(AHA);(CDC),,;12.5布点数量EN551--,,,,,,,,5m3,10;5~10m3,1m31;10m3,2m31,,2~3,,;;2~24RH30%~80%,33.1化学指示剂监测,,,,,,,[3],,,,3M(),(),3.2ISO对环氧乙烷灭菌化学指示剂其技术要求(1)(602),RH50%~70%,90min;(2)(60030)mg/L,RH50%~70%,(301),5min,30min[4]3.3工艺监测,,,;;;4,,,,,,,,:[1].[J].,2002,12(8):601-603.[2].[S].:,1991.12-14.[3].[J].,2002,12(9):690-691.[4].[S].,2000.17(1):50.3472003134