20146353JournalofCapitalMedicalUniversityJun.2014Vol.35No.3*CorrespondingauthorE-mailzhuangxiaoming101@163.com2014-06-0610∶16http∥.cnki.net/kcms/doi/10.3969/j.issn.1006-7795.2014.03.021.htmldoi10.3969/j.issn.1006-7795.2014.03.021··3*1000381147201210“1”CT“、”“”201212、、、+、2h1~2h10mmol/L。20d4U、4U、4U、、、10~15mmol/L8~14mmol/L。201314U、4U、4U、4U。。17.2kg/m29.3U/d4.8U1.5U、1.5U、1.5U0.21U/kg·d-14~8mmol/L6~10mmol/L。248“1”20134。B“”。CT“”。20135“、、、、+、”。。300mgQid。10.4U/d5.4U2U、1.5U、1.5U0.26U/kg·d-1。36620134、2、420135。6U、6U、6U4U4.6~13mmol/L3.3~12.7mmol/L4.1~13.9mmol/L、。6U、7U、5U3U21U/d〔0.3U/kg·d-1〕4~10mmol/L6~13mmol/L。21235≥11.1mmol/L≥7mmol/L2h≥11.1mmol/L。1999WorldHealthOrganizationWHO1“”2010AmericanDiabetesAssociationADA3Ctype3cdiabetesmellitusT3cDM12。2.1、、。。1943Rockey21。。、3Whipple。、、WhippleWhipple。、、40%~50%4-5。Maeda65%~42%0~8%100%。PPαβ。PP。2.2、。β。α。、。①②、③。①PP②。39.3~21.0U〔0.21~0.30U/kg·d〕。7617d154126~48U/d。33、。2.3447333、8-9。120U/d48U。。10mmol/L。6、、。、、。31AmericanDiabetesAssociation.DiagnosisandclassificationofdiabetesmellitusJ.DiabetesCare201033S62-S69.2RockeyEW.TotalpancreatectomyforcarcinomacasereportJ.AnnSug1943118603-611.3BillingsBJChristeinJDHarmsenWSetal.Quality-oflifeaftertotalpancreatectomyIsitreallythatbadonlong-termfollow-upJ.JGastrointestSurg2005981059-1067.4SlezakLAAnderDK.PancreaticresectioneffectsonglucosemetabolismJ.WorldJSurg200125452-460.5KingJKazanjianKMatsumotoJetal.DistalpancreatectomyincidenceofpostoperativediabetesJ.JGastrointestSurg2008121584-1533.6MaedaHHanazakiK.PancreatogenicdiabetesafterpancreaticresectionJ.Pancreatology201111268-276.7.6J.2013422187-188.8.J.20121571119-1121.9.J.201233179-83.2013-12-23573