三唑类杀菌剂竞争分析

先正达(中国)投资有限公司技术部叶承道三唑类杀菌剂竞争分析甾醇生物合成抑制剂作用方式研究概况1974抑制蛋白质合成1975抑制生物氧化作用1980抑制甾醇合成1980麦角甾醇Δ8-Δ7异构化作用1981麦角甾醇Δ14-还原作用1981麦角甾醇C14-脱甲基作用麦角甾醇生物合成抑制剂(EMIs)羊毛甾醇麦角甾醇2,4–亚甲基羊毛甾醇4,4–二甲基麦角甾-8,4,24三烯醇粪甾醇4,4二甲基粪甾醇14还原反应87双键异构化反应真菌细胞膜xxxC14-脱甲基反应14(15)还原酶/8(7)异构酶抑制剂A,吗啉类(Morpholines)R1=C12H25(dodemorph)十二环吗啉(1965)BASFONRR2=C13H27(tridemorph)十三吗啉(1965)BASFR3=C3H7-C6H5-C4H9(fenpropimorph)丁苯吗啉(1979)BASF烯酰吗啉,安克(dimethomorph)-(1984)Rohm&Hass丁苯吗啉(fenpropimorph)杀菌谱01020304050607080白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)14(15)还原酶/8(7)异构酶抑制剂B,哌啶类(Piperidines)CNRfenpropidin(Patrol)丁苯哌啶(1979)Roche-Maag甾醇C14a-脱甲基酶抑制剂(DMIs)A,嘧啶类(Pyrimidines)NCYCCCOHNCXX=H,Y=Cl苯嘧啶醇(triarimol,Elacocide)1975EliLiiiy/DowX=Cl,Y=H氯苯嘧啶醇(fenarimol,Rubigan)1976EliLilly/DowX=F,Y=H氟苯嘧啶醇(nuarimol)1976EliLilly/DowA,嘧啶类(Pyrimidines)杀菌谱乐必耕(fenarimol，Rubigan氯苯嘧啶醇)020406080100白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)B,吡啶类(Pyridines)CCClCCCOHNCCl帕里醇(Parinol)1976EliLilly/DowC,咪唑类(Imidazoles)CCNRNCOC3H5R=CH2CHCllC抑霉唑(imazalil,Fungflor,万得利)1972JanssenC,咪唑类(Imidazoles)ClOC2H4OClR=CNClC3H7咪鲜胺(prochloraze,Sportak施保克)1977,Schering/AventisCFNClR=CCH2OC3H7氟菌唑(triflumizole,Trifumine,特富灵)1979,NipponSodaC,咪唑类(Imidazoles)杀菌谱施保克(prochloraz,Sportak,咪鲜胺)0102030405060708090白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)D1,三唑类(Triazoles)CNNR1NCR1=CCF3三氟苯唑(fluotrimazole,Persalon,氟霉唑)1973,BayerD2,三唑类(Triazoles)CNNCHOCl(R)NCCC(CH3)3O三唑酮(Triadimefon,Bayleton,粉锈宁)1972,BayerCNNCHOCl(R)NCCHC(CH3)3HO三唑醇(triadiminol,Baytan,)1972,BayerD2,三唑类(Triazoles)杀菌谱三唑酮(tridimifon)020406080100白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)D2,三唑类(Triazoles)R=双苯三唑醇(bitertanol)1981,BayerClR=ClCH2苄氯三唑醇(diclobutrazole)1981,ICI/Zeneca/Syngenta*多效唑(Paclobutrazol,PP333)1981ClR=ClCH烯唑醇(diniconazole,Spotless,速保利)1982,Sumitomo**烯效唑(uniconazol,Sumagic)1982,D3,三唑类(Triazoles)CNOHNCH2CR2NCR1R1=ClC2H4,R2=(CH3)3C戊唑醇(tebuconazole,Raxil,立克秀,Folicur)1981,BayerFR1=F,R2=粉唑醇(flutriafol,Imapact)1983,ICI/Zeneca/SyngentaClR1=Cl,R2=nC4H9己唑醇(hexaconazole,Anil,安福)1985,ICI/Zeneca/SyngentaD3,三唑类(Triazoles)杀菌谱立克秀(tebuconazol,Raxil,Folicur戊唑醇)020406080100白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)D3,三唑类(Triazoles)杀菌谱安福(hexaconazole,Anvil,己唑醇)0102030405060708090白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)D4,三唑类(Triazoles)CNCNNCH2CR2NCR1R1=,R2=nC4H9咪菌腈(fenapanil,Sisthan)1976,Rohm-HaasR1=Cl,R2=nC4H9腈菌唑(myclobutanil,Systhane,仙生)1981,Rohm-HassR1=,R2=CF3C2H4唑菌腈(propanenitrile,RH7592)1988,Rohm-HassD5,三唑类(Triazoles)杀菌谱仙生(Myclobutanil,Systane,腈菌唑)0102030405060708090白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)D5,三唑类(Triazoles)ClCNNCH2CR2NCOOCCR1R1=CH3-甲环唑1978,Ciba/Novartis/SyngentaR1=C2H5-乙环唑(etaconazole)1978,Ciba/Novartis/SyngentaR1=n-C3H7–丙环唑(propiconazole,Tilt)1979,Ciba/Novartis/SyngentaClR1=CH3-,R2=-C--O--Cl苯醚甲环唑(difenoconazole,Score,世高)1983,Ciba/Novartis/SyngentaD5,三唑类(Triazoles)杀菌谱敌力脱(propiconazole,Tilt,丙环唑)020406080100白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)020406080100白粉病(ERYSIPHE)斑枯病(Septoria)条纹病(Pyrenophora)花腐病(Molinia)菌核病(Sclerotinia)黑星病(Venturia)叶斑病(Cercospora)散黑穗(USTILAGO)锈病(Puccinia)立枯病(Rhizoctonia)根腐病(Pellicularia)炭疽病(COLLETOTRICHUM)早疫病(Alternaria)稻瘟病(Pyricularia)枯萎病(Fusarium)茎枯病(Verticillium)灰霉病(Botrytis)D5,三唑类(Triazoles)杀菌谱世高(difenoconazole,Score)D5,世高(Score)对蔬菜白粉病(Erysiphe白粉菌)(Sphaerotheca单丝壳菌)和(Leveillula鞑靼内丝菌)的效果0102030405060708090100药效(%)豇豆，菜豆(Erysiphepolygoni)白菜(E.cruciferarum)胡萝卜，芫荽(E.unbelliferae)豌豆(E。Pisi)黄瓜