金钗石斛功能性成分及保健食品开发研究现状_李明元

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,:20143312ReserachStatusonFunctionalIngredientsandHealthCareFoodofDendrobiumnobileLindlLIMingyuan1,2,DENGWeize1,TANGXianfu2,YANGWenyu1,YANTianlong1,GUXia1(1.ProvincialKeyLaboratoryofFoodBiotechnologyofSichuan,CollegeofBioengineering,XihuaUniversity,Chengdu610039,China;2.XianCaoBiologicalTechnologyCoLtdChishuiGuizhou,Chishui564700,China)Abstract:DendrobiumnobileLindl.(Orchidaceae),arareChineseherbalmedicine,containsrichfunctionalingredients,suchasalkaloids,polyphenols,polysaccharides.Ithasbecomeahotspotofresearchinthefieldofmodernmedicaltreatment,healthcarefood,etc.Thisreviewsummarizestheresearchprogressesontheextraction,detection,structuralidentificationandfunctionalingredients.ThedevelopmentstatusonhealthcarefoodofD.nobile,whichshowsthatDendrobiumnobileLindl.hasdepthdevelopmentprospects.Keywords:Dendrobiumnobile,functionalingredients,healthcarefood:,,、、,、。、、,。:;;:TS201.4:A:1673—1689(2014)12—1233—061,2,1,2,1,1,1(1.,,610039;2.,564700):2014-03-25:(201306)。:(1965—),,,,,。E-mail:limingyuan519@qq.com(D.nobileLindl.),、,(Orchidaceae)(DendrobiumSw.),,《》,、、、。,、、、、、[1],。、,、,、。,1233LIMingyuan,etal:ReserachStatusonFunctionalIngredientsandHealthCareFoodofDendrobiumnobileLindlJournalofFoodScienceandBiotechnologyVol.33No.122014Review、、,。201310,,、、。。1.11.1.1,[2-4],,。、;、、、,[5][6]。1。1Table1Detectionmethodsofpolysaccharidecontent1.1.2,[7],DNP-W,DNP-WDEAE-,7DNP-W1A,DNP-W1B,DNP-W2,DNP-W3,DNP-W4,DNP-W5,DNP-W6。。,[8]DNP-W1B,DNP-W1B:DNP-W1B7.7×105,[α]D20=+81.3°(c0.3,H2O),、3,6.2∶3.1∶0.9。DNP-W1B1,4-1,6-,1,6-4,。,[7],[9],[10],K562[11],,(ConA)、(LPS)T、B[12],[13]、[14],[15]。1.21.2.1,,、、、;、、。,、、、、;、、、。。、[16]。、[17],70%,200W20min,l∶8(g/mL),,0.248%。2。2Table2Detectionmethodsofthetotaldendrobinecontent1.2.21932(Dendrobine)[18],1,,DNS、,Somogyi-Nelson-、、-,,、,1234,:20143312[19-20]:(dendrobine),(nobilonine),(dendrine),(dendroxine),(dendramine6-,6-hydroxydendrobine),6-(6-hydroxydendroxine),8-(8-hydroxydendroxine),noblimethylene,3--2-(3-hydroxy-2-oxodendrobine);5:N-(N-methyldendrobinium),N-(N-isopentenyldendrobiniumbromide),-N-(dendrobineN-oxide),N-(N-isopentenyldendroxiniumchloride)N--6-(N-isopentenyl-6-hydroxydendroxiniunchloride)。,(DendrobiumnobileLindl.Alkaloids,DNLA),。,DNLA[21-24]。,[25-26],[27-29]。[30],,。[31],iNOS(),。1.3Lee[32](denbinobin)Lusianthridin,4,7--2--9,10-(4,7-dihydroxy-2-methoxy-9,10-dihudrophenanthrene)。Lusianthridin。。Miyazawa[33],gigantolmoscatilin。Zhao[34]T、BdendrosideAdendronobilosidesA,T、BdendronobilosidesB。、[35]8,7,、,2-N-(2ˊ,3ˊ-dihydroxyhex-acosanoyl)-hexadecane-1,3,4-triol。[36]。lonchophylloidAB,,[37]。313,。(syringicacid)DPPH,VC。,,。19967,。,12953,709,。、,。()114,、。,3,、,34。3Table3CurrentsituationofmarketofthehealthcarefoodofDendrobiumnobile2//31111517192033222244441111111235LIMingyuan,etal:ReserachStatusonFunctionalIngredientsandHealthCareFoodofDendrobiumnobileLindlJournalofFoodScienceandBiotechnologyVol.33No.122014Review4Table4DevelopmentstatusofhealthcarefoodbrandsandfunctionaboutDendrobiumnobile:,。3,5856,,4;55951;。:(G20060563),(G20080243)、(20120229)、(G20120100)。34,,,。[38],0.46%,0.025%;3.8%,22%。,,,,、、。,,,;,;,。,,;,,。,。1998,([1998]17)。20063,。,2013,5.3,1.36。,GAP。,,,,。/111215019()311111:[1],,.—[J].,2002,21(4):36-37.GUANZhibing,LIZailin,LIEr.Arareandendangeredmedicinalplant:Dendrobiumnobile[J].ChineseWildPlantResources,2002,21(4):36-37.(inChinese)31236,:20143312[2],,,.[J].,2013,24(1):8-9.ZHANGYanlei,HEXiaoran,LIUYuanyuan,etal.StudyontheeffectofDendrobiumnobilepolysaccharidesonoxidativestressinratglomerularmesangialcellsculturedinhighglucose[J].ShizhenMedicineandMateriaMediaResearch,2013,24(1):8-9.(inChinese)[3],,,.[J].,2008,22(2):28-29.WEIXiaoyong,LONGYan,ZHANYujian,etal.StudyonthepreventionofcataractinratlensfromDendrobiumnobilelindlextractivesinvitro[J].ResearchandPracticeofChineseMedicine,2008,22(2):28-29.(inChinese)[4].TNF—α、NO[D].:,2008.[5],,.[J].,2002,23(10):50-51.GUOFei,XUShiying,LINZhichuan.Ultra-filtrationwasusedintheextrationofsargassumfusiformepolysaccharides[J].ScienceandTechnologyofFoodIndustry,2002,23(10):50-51.(inChinese)[6].[D].:,2004.[7].[D].:,2011.[8],,,.DNP-W1B[J].,2013,34(4):881-885.WANGJunhui,ZHAXueqiang,PANLihua,etal.StructuralcharacterizationofanimmunoactivepolysaccharideDNP-W1BfromDendrobiumnobileland[J].ChemicalJournalofChineseUniversities,2013,34(4):881-885.(inChinese)[9].[D].:,2011.[10],,,.[J].,2008,31(1):11-12.LIFei,HUANGQi,LIXiangyang,etal.EffectsoftheextractsfromDendrobiumnobileLindlonbloodsugarinnormalandhyperglycemicmice[J].ActaAcademiaeMedicineZunyi,2008,31(1):11-12.(inChinese)[11].K562[D].:,2009.[12],,,.[J].,2011,17(15):27-31.CHENZhiguo,YESongshan,FANYing,etal.OptimizationofextractiontechnologyofpolysaccharidefromDendrobiumnobileandeffectsonPro-liferationofmousesplenocytes[J].ChineseJournalofExperimentalTraditionalMedicalFormulae,2011,17(15):27-31.(inChinese)[13],,,.[J].:,2008,15(5):446-447.LIXiaoqiong,GEXiaojun,ZHENGSizhuo,etal.ExtractionofthePolysaccharidesfromDendrobiumnobileandsomephysicalandchemicalpropertiesanalysis[J].JournalofJiangsuUniversity:MedicineEdition,2008,15(5):446-447.(inChinese)[14].[D]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