2001心率变异Logistic-判别方程临床应用

Logistic(HRV)LogisticHRVSDNNSDANNSDNNIndexLogistic38(AMI),Logistic50%,(P01001)Logistic,HRVLogisticClinicalappliationofLogisticdiscriminantmodelinheartratevariabilityTANGHaiqin,LIANGQun,SHENGan,etal.TheFirstAffiliatedHospital,AnhuiMedicalUniversity,Hefei,230022AbstractObjectiveClinicalappliationofLogisticdiscriminantmodelandcomparisonbetweenLogisticmodelandsinglemeasuremethodofHRV.MethodsMakeuseofLogisticdiscriminantmodelformedfrommultiplemeasuresofHRV(SDNN,SDANNandSDNNIndex)andage,meanofheartratein24hourrecordingtodiagnose38patientsafteracutemyocardialinfarction,comparisonoftheresultsbetweenLogisticmodelandsinglemeasuremethod.ResultsPositiverateofLogisticmodelwas50percent,whichwassinginifcantlyhigherthanthatofsinglemeasuremethod(P0.001).ConclusionLogisticdiscriminantmodelformedfrommultiplemeasuresofHRVissuperiortothesinglemeasuremethodandwillbebeneficialtoclinicalappliationofHRV.KeywordsHeartratevariabilityLogisticmodelMyocardialinfarction(heartratevariability,HRV)[1,2]HRVHRV,,HRVLogistic,HRVHRV,1111Logistic,238,30,8;4588,69151013:18,11,911224h,DMS.Holter,2QRS,HRV:R2R(SDNN);(SADNN);(SDNNIndex);R2R(RMSSD);NN50R2R(PNN50)24h(MHR)113HRVHRV:SDNN50ms[3];:SDNN73ms,SDANN64ms,SDNNIndex26ms[4]Logistic[5]:P=exp(-018517-011317SDANN+010980SDNN+010781AGE-010350SDNNIndex-010296MHR)1+exp(-018517-011317SDANN+010980SDNN+010781AGE-010350SDNNIndex-010296MHR)PHRV,P=0150:230022,();();();();();();();(),P0150HRV,P0150HRV114EpiInfo(6102)LogisticSPSS/PC22322200112441Logistic(%)PLogistic015019193850100SDNN(ms)503632381517801001SDNN(ms)7333172138441740105SDANN(ms)6433182038471370105SDNNIndex(ms)2633830382110501001:3[3],33[4]211x-1164sHRV:SDNN=63,SDANN=55,SDNNIndex=23(ms),AGE=67(),MHR=72(bpm):P=014858780150:SDNN=62,SDANN=54,SDNNIndex=22(ms),AGE=67(),MHR=72(bpm)P=0150667520150Logisticx-1164s212LogisticHRV,HRV,38HRV:SDNN8738ms,SDANN7632ms,SDNNIndex4022ms,MHR7310bpm(RMSSD,PMN50,)HRVAGEMHRLogistic,1Logistic50100%,SDNN50ms15178%(P01001)HRV,SDANN31987KleigerHRV,HRV,,[1]HRV,,HRV,HRV,HRV,SDNNHRVHRV,,HRV,Logistic[6][7],Lo2gisticHRV,HRV,Logistic,HRV,HRVLogistic50%,,HRVHRV,Logistic,HRV,(:)1,11,1999,3:712TsujiH,VendittiFJ,MandersES,etal.Reducedheartratevariabilityandmortalityriskanelderlycohort:theframing2hamheartstudy.Circulation,1994,90:8783MalikM.Heartratevariability2standardsofmeasurement,physiologicalinterpretationandclinicaluse.Circulation,1996,93:10434,,,11,1998,17:25,,,1Logistic1,1999,27:686LanzaGA,PedratiP,RebuzziAG,etal.Vsefulnessoftheadditionofheartratevariabilitytoholtermonitoringinpre2dictingin2hospitalcardiaceventsinpatientswithunstableanginapedoris.AmJCardiol,1997,80:2637BovenAJ,JukemaJW,HaksmaJ,etal.Depressedheartratevariabilityisassociatedwitheventsinpatientswithstablecoronargartergdiseaseandpreservedleftventricularfunc2tion.AmHeartJ,1998,135:571422JClinHealthcare,December2001,Vol4No4