工作场所空气中挥发性有机物的GC_MS检测技术研究

[]　(A2006620);([2004]199)[]　(1968-),,,,。【】工作场所空气中挥发性有机物的GC/MS检测技术研究陈剑刚,谭爱军,张彩虹,白艳铃,黄辉涛(,　519000)[]　:54GC/MS。:,DB-VRX、-。:,;54,r≥0.99;,76%～102%。:、、,。[]　挥发性有机物;工作场所空气;气质联用;检测方法[]　R134　　　　[]　A　　　　[]　1004-8685(2008)06-0964-06StudyontechniqueforrapiddeterminationofvolatileorganiccompoundsinairinaworkplaceChenJian-gang,TanAi-jun,ZhangCai-hong,BaiYan-ling,HuangHui-tao(ZhuhaiCenterforDiseaseControlandPrevention,Zhuhai519000,China)[Abstract]　Objective:Toestablishagaschromatography-massspectrummethodforrapiddeterminationof54kindsofVOCsintheairinaworkplacebysolventdesorption.Methods:Fifty-fourVOCsintheairwasadsorptedbyactivatedcarbontubesam-plingandsolventdesorptionusingcarbondisulfa,thenseparatedbyGCwithanDB-VRXcapillarycolumnandanalyzedbyGC/MS.Results:Fifty-fourofVOCsareseparatedcompletelyfromeachotherandsimultaneouslyidentifiedandquantified.Thecor-relationcoefficientofthecurveswasgoodandgreaterthan0.99betweendefinedconcentrationrange.Detectionlimitwasmuchlowerthanpoisoningdosagelevelintheworkplaceair,withthedesorptionefficiencyof76%～102%.Conclusion:Themethodisaccurate,simple,sensitive,rapidandsuitabletoqualifyandquantifymixturesofVOCsintheairataworkplace.[Keywords]　VOCs;Workplaceair;GC/MS;Determinationmethod　　,。。WHO,(vola-tileorganiccompounds,VOCs),50℃～260℃,133.3Pa,。VOCs、、、、、、8,300。VOCs,。,、,、,[1]。,VOCs、54。VOCs(GC)、(HPLC)、(GC/MS),GCGC/MS[2]。,VOCs[3～5]。GC/MS,。,,。1　1.1　仪器GC/MS-QP5050A,GCsolution1.02,;TWA-300,20～500ml/min;GH-1,100mg/50mg;;5ml;。1.2　试剂(1)、,Riedel-dehaen,,99.9%;(2)VOCs,2000μg/ml,SUPELCO;(3):10ml,0.50mlVOCs,100μg/ml。96420086186　ChineseJournalofHealthLaboratoryTechnology,Jun2008;Vol18　No61.3　色谱条件DB-VRX(60m×0.25mm×1.40μm);:45℃,4min,4℃/min190℃,2min,6℃/min225℃,10min;:1.0ml/min,;,20:1;220℃;240℃。1.4　质谱条件:EI(70v);240℃;3min;35～280amu;1.1kv;500amu/s;0.4s。1.5　空气样品的采集及测定(≥2mm),,100ml/min15min,,。,1.0ml,,15min。2　2.1　色谱条件优化,,;,GC。54。,DB-5ms、DB-35ms、FFAP、DB-VRX。:,VOCs,60m×0.25mm×1.40μmDB-VRX,5460min,、(29#)1,1,2,2-(32#),50;、、。,DB-VRX,CS2。54VOCs1,2。1　54VOCsGC/MS2.2　快速定性指纹参数,MSD(SCAN),,,,。SCAN,(SIM)。(BPI)±20%,GC/MS。541。96520086186　ChineseJournalofHealthLaboratoryTechnology,Jun2008;Vol18　No61　54BPICAS#11,1-8.58196,61,9814675-35-4C2H2Cl29628.90184,49,8614275-09-2CH2Cl2843-1,2-10.33296,61,98140156-60-5C2H2Cl29641,1-10.88963,65,833275-34-3C2H4Cl2985-1,2-12.21896,61,98127156-59-2C2H2Cl296612.604128,130,4914474-97-5CH2ClBr128712.73083,85,476667-66-3CH3Cl11882,2-12.90877,79,9734594-20-7C3H3Cl211291,2-14.36962,98,6416107-06-2C2H4Cl298101,1,1-14.61197,99,616471-55-6C2H3Cl3132111,1-15.10875,110,7736563-58-6C3H4Cl21101215.554117,119,1219856-23-5CCl41521315.68778,77,522471-43-2C6H6781417.24693,174,955274-95-3C2H2Br2172151,2-17.37263,62,767678-87-5C3H6Cl21121617.484130,95,1328679-01-6C2HCl31301717.62583,85,476475-27-4CHBrCl216218-1,3-19.56575,77,1103110061-02-6C3H4Cl211019-1,3-20.92575,77,1106310061-01-5C3H4Cl2110201,1,2-21.39383,97,8510879-00-5C2H3Cl31322121.98091,92,6560108-88-3C7H892221,3-22.15876,77,419142-28-9C3H6Cl2972322.958129,127,13170124-48-1CHBr2Cl206241,2-23.752107,109,2797106-93-4C2H4Br21862524.346166,164,129,13170127-18-4C2Cl4164261,1,1,2-26.394131,133,11798630-20-6C2H2Cl41662726.646112,77,11467108-90-7C6H5Cl1122827.41191,10632100-41-4C8H1010629/28.110106,91,105125106-42-3/108-38-3C8H101063028.352173,175,2525275-25-2CHBr32503129.253104,78,10348100-42-5C8H810432/1,1,2,2-29.498106,91/131,13320995-47-6/79-34-5C8H10/C2H2Cl4106/168331,2,3-29.96975,110,973396-18-4C3H5Cl1463430.852105,120,792798-82-8C9H121203531.609156,158,7799108-86-1C6H5Br1563632.47891,120,10514103-65-1C9H12120372-32.74191,126,892395-49-8C7H7Cl126384-33.05391,126,12523106-43-4C7H7Cl126391,3,533.639105,120,11995108-67-8C9H121204034.604119,91,1343698-06-6C10H14134411,2,4-35.066105,120,912295-63-6C9H121204235.427105,134,9119135-98-8C10H14134431,3-35.600146,148,11163541-73-1C6H4Cl2146441,4-36.860146,148,11164106-46-7C6H4Cl21464536.179119,134,912899-87-6C10H14134461,2-37.174146,148,1116395-50-1C6H4Cl21464737.73191,92,13460104-51-8C10H14134481,2--3-38.957157,75,15511996-12-8C3H5Br2Cl234491,2,4-44.451180,182,14594120-82-1C6H3Cl31805045.393128,127,1021291-20-3C10H81265145.735225,227,2607587-68-3C4Cl6258521,2,3-46.188180,182,1459387-61-6C6H3Cl318096620086186　ChineseJournalofHealthLaboratoryTechnology,Jun2008;Vol18　No62.3　定量参数表MSD。,,。,SIM,SIM2。2　54SIMStarttime(min)Endtime(min)Ch1-m/zCh2-m/zch3-m/zch4-m/zch5-m/zch6-m/zch7-m/zch8-m/zch9-m/zch10-m/zch11-m/zch12-m/zch13-m/zch14-m/z13.009.5096.0061.0084.0049.000.000.000.000.000.000.000.000.000.000.0029.5011.5096.0061.0063.0065.000.000.000.000.000.000.000.000.000.000.00311.5013.8096.0061.00128.00130.0083.0085.0077.0079.000.000.000.000.000.000.00413.8016.5062.0098.0097.0099.0075.00110.00117.00119.0078.0077.000.000.000.000.00516.5018.5093.00174.0063.0062.00130.0095.0083.0085.000.000.000.000.000.000.00618.5020.3075.0077.000.000.000.000.000.000.000.000.000.000.000.000.00720.3025.3075.0077.0083.0097.0091.0092.0076.0077.00129.00127.00107.00109.00166.00164.00825.3028.80131.00133.00112.0077.0091.00106.00106.0091.00173.00175.000.000.00