生物技术药物-抗体药物

朱俊铭朱俊铭朱俊铭朱俊铭朱俊铭朱俊铭朱俊铭朱俊铭20112011201120112011201120112011年年年年年年年年1010101010101010月月月月月月月月生物技术药物生物技术药物生物技术药物生物技术药物生物技术药物生物技术药物生物技术药物生物技术药物主要内容主要内容主要内容主要内容主要内容主要内容主要内容主要内容绪论绪论绪论绪论绪论绪论绪论绪论动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　动植物细胞培养生产医药用产品或原料　　转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器转基因动植物作为药物生物反应器抗体工程药物抗体工程药物抗体工程药物抗体工程药物抗体工程药物抗体工程药物抗体工程药物抗体工程药物干细胞与治疗性克隆干细胞与治疗性克隆干细胞与治疗性克隆干细胞与治疗性克隆干细胞与治疗性克隆干细胞与治疗性克隆干细胞与治疗性克隆干细胞与治疗性克隆基因工程疫苗与基因工程疫苗与基因工程疫苗与基因工程疫苗与基因工程疫苗与基因工程疫苗与基因工程疫苗与基因工程疫苗与DNADNADNADNADNADNADNADNA疫苗疫苗疫苗疫苗疫苗疫苗疫苗疫苗基因药物基因药物基因药物基因药物基因药物基因药物基因药物基因药物反义核酸与反义技术反义核酸与反义技术反义核酸与反义技术反义核酸与反义技术反义核酸与反义技术反义核酸与反义技术反义核酸与反义技术反义核酸与反义技术生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术药物新药与专利申报生物技术制药产业化个案生物技术制药产业化个案生物技术制药产业化个案生物技术制药产业化个案生物技术制药产业化个案生物技术制药产业化个案生物技术制药产业化个案生物技术制药产业化个案抗体工程药物抗体工程药物单克隆抗体与基因工程抗体单克隆抗体与基因工程抗体单克隆抗体与基因工程抗体单克隆抗体与基因工程抗体抗体制备技术抗体制备技术抗体制备技术抗体制备技术抗体药物现状和趋势抗体药物现状和趋势抗体药物现状和趋势抗体药物现状和趋势INDEXINDEXINDEXINDEXINDEXINDEXINDEXINDEX单克隆抗体与基因工程抗体单克隆抗体与基因工程抗体单克隆抗体与基因工程抗体单克隆抗体与基因工程抗体抗体制备技术抗体制备技术抗体制备技术抗体制备技术抗体药物现状和趋势抗体药物现状和趋势抗体药物现状和趋势抗体药物现状和趋势INDEX抗体特性抗体特性抗体特性抗体特性抗体特性抗体特性抗体特性抗体特性��AntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyAntibodiesareproteinsproducedbyBcellsBcellsBcellsBcellsBcellsBcellsBcellsBcellsininininininininresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmoleculesresponsetothepresenceofforeignmolecules((((((((proteins,tumors,virusesproteins,tumors,virusesproteins,tumors,virusesproteins,tumors,virusesproteins,tumors,virusesproteins,tumors,virusesproteins,tumors,virusesproteins,tumors,virusesandandandandandandandandbacteriabacteriabacteriabacteriabacteriabacteriabacteriabacteriaest.)inthebodyest.)inthebodyest.)inthebodyest.)inthebodyest.)inthebodyest.)inthebodyest.)inthebodyest.)inthebody��AntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebodyAntibodiesareimportantpartsofthebody’’’’’’’’simmunesimmunesimmunesimmunesimmunesimmunesimmunesimmunedefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstodefensesystem,actingasbiologicalwarheadstoeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebodyeliminateforeignorabnormalagentsfromthebody��EachantibodyisEachantibodyisEachantibodyisEachantibodyisEachantibodyisEachantibodyisEachantibodyisEachantibodyishighlyspecifichighlyspecifichighlyspecifichighlyspecifichighlyspecifichighlyspecifichighlyspecifichighlyspecifictoitsantigentoitsantigentoitsantigentoitsantigentoitsantigentoitsantigentoitsantigentoitsantigen��AllantibodiessharethesamebasicAllantibodiessharethesamebasicAllantibodiessharethesamebasicAllantibodiessharethesamebasicAllantibodiessharethesamebasicAllantibodiessharethesamebasicAllantibodiessharethesamebasicAllantibodiessharethesamebasicYstructureYstructureYstructureYstructureYstructureYstructureYstructureYstructure��EachantibodycontainssixdistinctEachantibodycontainssixdistinctEachantibodycontainssixdistinctEachantibodycontainssixdistinctEachantibodycontainssixdistinctEachantibodycontainssixdistinctEachantibodycontainssixdistinctEachantibodycontainssixdistinctCDRCDRCDRCDRCDRCDRCDRCDRregions(CDR1,regions(CDR1,regions(CDR1,regions(CDR1,regions(CDR1,regions(CDR1,regions(CDR1,regions(CDR1,CDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinityCDR2,CDR3)forbindingspecificityandaffinity��MajorclassesofantibodiesareMajorclassesofantibodiesareMajorclassesofantibodiesareMajorclassesofantibodiesareMajorclassesofantibodiesareMajorclassesofantibodiesareMajorclassesofantibodiesareMajorclassesofantibodiesareIgGIgGIgGIgGIgGIgGIgGIgG(1,2,3,4),(1,2,3,4),(1,2,3,4),(1,2,3,4),(1,2,3,4),(1,2,3,4),(1,2,3,4),(1,2,