,,,,,,,,,!,,,,,,!!∀#,sureandthereforetheeapitaleostaswellastheoperatingeostassoeiatedwithHDSveryhigh.Biologiealdesulfurizationhasthepotentialofbeingdevel-opedasaviableteehnologydownstreamof6lassiealHDs.variousattemptshavebeenmadetodevelopbioteehno-logiealproeessesbasedonmierobiologiealdesulfurizationemployingaerobieandanaerobiebaeteria.However,thereareseveralbottleneekslimitingeommereializationoftheproeess.Thisreviewdiseussesvariousaspeetsofmierobialdesulfurizationand.theprogressmadetowardsitseommereiali:ation,,,,,,,,,,,,,,,,,,,,,,,,,HDS,,,,,,,,,,,,1,,,,,,,,,,pH,,,C,C,,,,,DBT,2,BdsC,BdsA,,BdsA,,,,,,,,,,,,P.putida[9],,,,,,HFBT,3,HFBT,DBT,4,7,7-,3,6,,Kodama,DBT,,,,Desulfovibriosp.,,,HZS,D.longrea,,,,,,,,,10,,,DszA),,,,RhodoeoeeusECRDI,RhodoeoeeusBl,GordonaCYKSI,Paenibaeillus,,,,,,,,,,,,,,,,,,,R.rhodoehrousIGTSS,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,1978[,,2005,1:23,IshiiY,MatsubaraT,etal.Diben:othiophenedesulfurizingenzymesfrommoderatelythermoPhiliebaeteri-um13aeillussubtilisWU,eharaeterizationandoverexpression,2005,100(3):266,AlvianonDS,AlvianonCS,etal.CharaeterizationofGordoniasp.strainF.5.25.8caPableofdiben,2005,7:l,,,,2005,29(1):111,,,,2005,15(1):65,NakatiniS,UmeharaK,etal.(1970)MierobialeonversionofPetro,1970,34:1320,BakkerD,FinnertyWR.Plasmidmediateddegradationofdibenzothiophenebypseudomonassp[J,1985,49:756,AtlasRM.Biotransformationofdibenzothio-phenetodibenzothiophenesulfonebyPseudomonasputida.CanJMierobiol,1989,35:603,1990,21:229,HadarY,FuPP,etal.Initialoxidationproduetsinthemetabolismofpyrene,anthraeene,fluorine,anddiben-zothiophenebythewhiterotfungusPleurotusostreatus.Ap-plEnvironMierobiol,1996,62:2554,2559,,