电渗析技术在氨基酸生产中的应用陈艳

[1]、、、。[2]。、、。－COOH－NH2。pHpHApHC。、。2050[3]。[4]、[5]、[6][7]、[8]。、。1、。、、。1.1。L-[9]。L-L-1。L-621010。。TQ028.8A1000-3770(2011)11-0010[e-mail]1Fig.1Schematicofthetwo-compartmentelectrodialyzer3711201111TECHNOLOGYOFWATERTREATMENTVol.37No.11Nov.,201110DOI:10.16796/j.cnki.1000-3770.2011.11.0030.5mol·L-1H2SO4L-L-。L-、、、、。、、、。1.21.2.1C-A[10]。2pH。Na+、Cl-Na+Cl-95.5%。8、。GribH[11]18h98%Na2SO4(NH4)2SO4。LiuLifen[12]15%NaClL-L-。L-60.4%98%。[13]L-L-。、。。C-A。3AA+AA-AA0。BukhovetsAE[14]。pH5.63、。[15]5%Na2SO424h。1.2.2C-CL-。KumarM[16]4。、96%73%。。90%2C-AFig.2Schematicofthethree-compartmentelectrodialyzer(C-A)forseparationofaminoacidandinorganicsalt3C-AFig.3Schematicofthethree-compartmentelectrodialyzer(C-A)forseparationofmixedaminoacids4C-CFig.4Schematicofthethree-compartmentelectrodialyzer(C-C)11。。pH、。1.31.3.1C-A-C[17]L-Lys·HClNaOH、Na2SO4L-Lys·HClL-Lys。5、、。L-Lys·HCl0.3mol·L-1L-Lys·HClNaOH3530VpHL-Lys9.74Cl-L-Lys73.1%86.4%。[18]MC。。。DL-[19]。DL-α-20%～40%10%70%60%70%。1.3.2A-A-CZhangYP6L-Lys·HClCl-L-Lys[20]。40VL-Lys·HCl0.6mol·L-1pH9.74Cl-95.6%。A-A-CCl-Cl-Cl2。[21]HF101、HF201。。1.3.3A-C-AL-γ-。、[22]7。pH95%76%85%。HHabe[23]γ-GABA50g·L-1GABApH=3GABA85%。2BMC、A。7A-C-AFig.7Schematicofthefour-compartmentelectrodialyzer(A-C-A)6A-A-CFig.6Schematicofthefour-compartmentelectrodialyzer(A-A-C)5C-A-CFig.5Schematicofthefour-compartmentelectrodialyzer(C-A-C)371112[24]。。、。2.12.1.1BM-C-BM2-。[25]8。8%～16%96%10%。50%2kWh·kg-1。[26]。Na+80%20%～50%。2.1.2BM-A-BM。[27]9。SO42-、。、。、[28]。85.4%0.196kWh·m-3。、[29]。、。2.2。、[30]1096%。。。[31]。[32]。。310BM-A-C-BMFig.10Schematicofthefive-compartmentbipolarmembraneelectrodialyzer(BM-A-C-BM)9BM-A-BMFig.9Schematicofthefour-compartmentbipolarmembraneelectrodialyzer(BM-A-BM)8BM-C-BMFig.8Schematicofthefour-compartmentbipolarmembraneelectrodialyzer(BM-C-BM)13、。、、。、、、、。、。。。。。、EDI。。。、、、pH。EDI。EDI。。EDI。[1],.[J].,2008,37(7):8-30.[2],.[J].,2002,4:72-73.[3],,,.[J].,2001,2(3):44-47.[4],,.[J].,2003,13(4):20-31.[5]MelnykL,GoncharukV.ElectrodialysisofsolutionscontainingMn(II)ions[J].Desalination,2009,241(3):49-56.[6],,.[J].,1991,19(1):49-55.[7]VeraE,SandeauxJ,PersincF,etal.Deacidificationofpassionfruitjuicebyelectrodialysiswithbipolarmembraneafterdifferentpre-treatments[J].JournalofFoodEngineering,2009,90(1):67-73.[8],.[J].,2002,28(5):288-290.[9],.[J].,1999,3:46-50.[10],.[J].,1995,17(1):13-15.[11]GribH,BelhocineD.Desaltingofphenylalaninesolutionsbyelec-trodialysiswithion-exchangemembranes[J].JournalofAppliedElectrochemistry,2000,30(3):259-262.[12]LiuLifen,YangLanlan,JinKeyong,etal.RecoveryofL-tryptophanfromcrystallizationwastewaterbycombinedmembraneprocess[J].SeparationandPurificationTechnology,2009,66(3):443-449.[13],,,.L-[J].,1995,3:25-27.[14]BukhovetsAE,Savel'evaAM,EliseevaTV.Separationofaminoacidsmixturescontainingtyrosineinelectro-membranesystem[J].Desalination,2009,41(2):68-74.[15],,.[J].:,1999,27(2):65-69.[16]KumarM,TripathiBP,ShahiVK.Electro-membranereactorforseparationandinsituionsubstitutionofglutamicacidfromitssodiumsalt[J].ElectrochimicaActa,2009,54(21):4880-4887.[17]ChenY,ZhangYP,YueMZ,etal.ProductionofL-lysinefromL-lysinemonohydrochloridebyelectrodialysis[J].DesalinationandWaterTreatment,2011,25:291-296.[18],.[J].,2001,1:19-20.[19],,.DL-[J].,2002,24(2):34-36.[20]ZhangYP,ChenY,YueMZ,etal.RecoveryofL-lysinefromL-lysinemonohydrochloridebyionsubstitutionusingion-exchangemembrane[J].Desalination,2011,271:163-168.[21],,.[J].,1999,21(3):49-51.[22]ShenJinyu,DuanJingran,LiuYuanshuai,etal.Demineralizationofglutaminefermentationbrothbyelectrodialysis[J].Desalination,2005,172(2):129-135.[23]HabeH,YamanoN,TakedaS,etal.Useofelectrodialysistosepa-rateandconcentrateγ-aminobutyricacid[J].Desalination,2010,253(3):101-105.[24],,,.[J].,2004,23(10):1107-1112.[25],,.[J].,2002,2:15-16.[26]YuLixin,SuJing,WangJun.Bipolarmembrane-basedprocessfortherecycleofp-toluenesulfonicacidinD-(-)-p-hydroxyphenyl-glycineproduction[J].Desalination,2005,177(30):209-215.[27]ZhangXiaoyan,LuWenhua,RenHongyan,etal.Recoveryofglu-tamicacidfromisoelectricsupernatantusingelectrodialysis[J].SeparationandPurificationTechnology,2007,55(2):274-280.[28],.[J].,2003,4(2):33-35.[29],.[J].,2007,26(6):882-885.[30],.[J].:,2004,44(12):1588-1591.[31],.[J].,2005,25(5):21-25.[32],,.[J].,2009,60(5):1199-1203.37112514[2]AvnimelechY,Bio-filters.Theneedforanewcomprehensiveapproach[J].AquaculturalEngineering,2006,34:172-178.[3]WangJK.Conceptualdesignofamicroalgae-basedrecirculatingoysterandshrimpsystem[J].AquacEng.,2003,28(1-2):37-46.[4]Gutierrez-WingMT,MaloneRF.Biologicalfiltersinaquaculture:trendsandresearchdirectionsforfreshwaterandmarineapplica-tions[J].AquacEng.,2006,34(3):163-171.[5]TimmonsMB,EbelingJM.Theroleforrecirculatingaqua-culturesystems[J].AESNews,2007,10(1):2-9.[6]HargreavesJA.Photosyntheticsuspended-growthsystemsinaqua-culture[J].AquacultureEngineering,2006,34:344-363.[7]SchneiderO,SeretiV,EdingEH,etal.Analysisofnutrient￡owsinintegratedintensiveaquaculturesystems[J].AquacultureEngi-neering,2005,32:379-401.[8]GoldmanJC,CaronDA