搜索
HighTemperature,Pressure,ThroughputMicro-channelReactor第二届微化工技术研究与行业应用及工艺优化工程设计研讨会,8/24/2018楊立勔(BarryYang)瑞林科技(RichlinkTechnologyConsulting)Aug2018BarryYang,RichlinkConsulting2OutlinePlatetypemicro-channelreactorbeingcommercializedsuccessfully–ParticularlyforpharmaceuticalandfinechemicalproductionUpgradingfromplatetype(2D)tocubetype(3D)micro-channelreactor–Enablinghightemperature,highpressureapplications–Ordersofmagnitudegreaterthroughput,withhigherprocessintensificationManufacturingcubetypemicro-channelreactorTechnicalandbusinesschallengesVelocysGTLasacommercialexampleSummaryAug2018BarryYang,RichlinkConsulting3Micro-channelReactorProvidesMuchImprovedTemperatureControlvs.CorningAFRTMbrochureAug2018BarryYang,RichlinkConsulting4StaticMixerReplacestheMovingStirrerCorningAFRTMbrochure,2016CorningheartshapedstaticmixerAug2018BarryYang,RichlinkConsulting5SelectiveHydrogenationofSlurryinCorningAFRTMwith98%+ConversionandSelectivityCorningAFRTMpresentation,Woehl,2010Aug2018BarryYang,RichlinkConsulting6AdvantagesofMicro-channelReactorProcessintensification–Upto100XintensificationdemonstratedHigherenergyefficiencyMuchsaferoperation(intrinsicsafety)–Minimalchemicalhold-up–Characteristicsofaflamearrester–Usuallynomovingparts(suchasstirrers)tocausemechanicalbreakdown,littlevibrationOperatingwindowcanoftenbewidenedsafelyProcesscontrolinherentlybetterAssuredscale-up(numberingup)Aug2018BarryYang,RichlinkConsulting7ProcessIntensificationEnhancedheattransfer–Muchlargerheattransferarea–Shorterheattransferdistance(mmorless)Enhancedmasstransfer–StaticmixerEnhancedreactionkinetics–Canraisetemperatureandpressuretobeyondconventionalbecausedeviceisinherentlysafe–TighterreactionspacemeansmuchbettercontrolledtemperatureandconcentrationprofilesMuchbetterprocesscontrolforimprovedyieldAug2018BarryYang,RichlinkConsulting8DisadvantagesofMicro-channelReactorHigherpressuredrop–DuetochannelsizebeingsmallLimitedcompatibilitywithsolidparticulates–Particulatescouldcausechannelclogging,whichmayfurtherimpactpressuredropandflowdistributionMaynotbesuitableforreactionswithheavyprecipitationAlthoughrecentdevelopmenthassuccessfullydemonstratedprocessingslurrieswithupto30%solidcontentHighreactorcost–Duetotheneedforfineengineeringandprecisionmanufacturing–ButtotalcosttomarketisoftenmuchlowerAug2018BarryYang,RichlinkConsulting9BenefitsofMicro-channelReactorShortertimetomarket–AcceleratedprocessR&D,optimization,andscale-upNon-traditionalprocessingenabled–Practical,safer,on-site,on-demandproduction–Portable,smallfootprint,modular/skiddesign–Canintegratemultipleoperationsinto1unit–Dedicateddeviceforassignedreaction,avoidingcrosscontamination–Canhandlesomemulti-phasereactionseffectivelyOverallcostreduction–ReducedR&Dandscale-upcosts–LowerOPEX(higheryield,higherthroughput,lesssolvent,lesswaste...)Aug2018BarryYang,RichlinkConsulting10SomeKeyPlayersinCommercializingPlateTypeMicro-channelReactorCorningAFRTMChemtrix豪邁化工貴州微化科技紹興東湖高科(EhrfeldMikrotechnik)清華大學大連化物所微化工技術組南京工業大學綠色化工Aug2018BarryYang,RichlinkConsulting11LimitedOperatingTemperatureandPressureofPlateType(2D)Micro-channelReactorMaxtemperature(C)Maxpressure(bar)Corning20018豪邁化工20055Chemtrix20016貴州微化科技2005005010015020002004006008001000Temperature,CPressure,barBasedonpublishedspecificationsofindustrialsizereactorsofferedoncompanywebsitesTheneedofusingO-ringorgasketforsealinglimitsoperatingtemperatureto300CAug2018BarryYang,RichlinkConsulting12UpgradingMicro-channelReactorTakeoutO-ringorrubbergaskettoenablehightemperatureservicesMetalconstructiontoallowhighpressureoperationsImprovedesignforhighthroughputandgreaterprocessintensificationAug2018BarryYang,RichlinkConsulting13PlateType(2D)vs.CubeType(3D)Micro-channelReactor2thermalcontrollayersforeachreactionlayer~1thermalcontrollayerforeachreactionlayerPlateType(2D)CubeType(3D)Cubetype(3D)micro-channelreactorhasmuchimprovedlayerutilizationandenergyefficiencyCorningAFRTMbrochureThermalcontrollayerReactionlayerAug2018BarryYang,RichlinkConsulting14ChannelLayoutAffectsPackingDensityandProcessIntensificationCorningAFRTMbrochure,2016US2014/0264175A1Dense,parallelchannelsforhigherthroughputandprocessintensificationCorningchannellayoutVelocyschannellayoutAug2018BarryYang,RichlinkConsulting15UsingSurfaceFeatureasStaticMixerUS2011/0002818A1Crosssectionofamicro-channelAug2018BarryYang,RichlinkConsulting16SomeExamplesofSurfaceFeatureasStaticMixerMixingachievedbyforcingthefluidtoflowoversurfacefeaturesSurfacefeaturesalsoaddsurfaceareas,advantageousforcatalystcoating,ifneededEP2543434A1Aug2018BarryYang,RichlinkConsulting17PlateType(2D)vs.CubeType(3D)Micro-channelReactorHeatricBrochureCorningAFRTMpresentation,Woehl,2010PlateType(2D)CubeType(3D)Notechannelsplittingto4XmaxHundredsandthousandsofparallelchannelsThemoretheparallelchannels,thelowerthepressuredropAug2018BarryYang,RichlinkConsulting18LookingintoaCuteType(3D)Micro-channelDeviceHeatricheatexchanger,typicallymadeofstainlesssteel=Heatric+micro+heat+exchanger+images&rlz=1CAACAV_enUS702TW710&tbm=i