sci审稿意见回复范文

论文题目：PharmacokineticandpharmacodynamicstudiesontheantiviruseffectsofA(一种中草药)againstvirusB（一种病毒）所投杂志：LifeSciences投稿结果：这次大修后又经过一次小修，被接受发表编辑信内容（注：有删节）：DearMr.XXX,Yourmanuscripthasbeenexaminedbytheeditorsandqualifiedreferee.WethinkthemanuscripthasmeritbutrequiresrevisionbeforewecanacceptitforpublicationintheJournal.Carefulconsiderationmustbegiventothepointsraisedinthereviewercomments,whichareenclosedbelow.Ifyouchoosetosubmitarevisionofyourmanuscript,pleaseincorporateresponsestothereviewercommentsintotherevisedpaper.Acompleterebuttalwithnomanuscriptalterationsisusuallyconsideredinadequateandmayresultinlengthyre-reviewprocedures.Aletterdetailingyourrevisionspoint-by-pointmustaccompanytheresubmission.YouwillberequestedtouploadthisResponsetoReviewersasaseparatefileintheAttachFilesarea.Weaskthatyouresubmityourmanuscriptwithin45days.Afterthistime,yourfilewillbeplacedoninactivestatusandafurthersubmissionwillbeconsideredanewmanuscript.Tosubmitarevision,gotoandloginasanAuthor.YouwillseeamenuitemcalledSubmissionNeedingRevision.Youwillfindyoursubmissionrecordthere.Yourssincerely,JosephJ.Bahl,PhDEditorLifeSciencesFormatSuggestion:PleaseaccesstheGuidetoAuthorsatourwebsitetochecktheformatofyourarticle.PayparticularattentiontoourReferencesstyle.Reviewers'comments:Reviewer#1:XXXXX（略）Reviewer#2:XXXXX（略）Editorsnoteandsuggestions:（注：编辑的建议）Title:Re-writethetitletoreadmoresmoothlyincontemporaryEnglishPharmacokineticandpharmacodynamicstudiesoftheantiviraleffectsofAagainstvirusB.Abstract:Re-writetheabstracttoreadmoresmoothly.A,analkaloidisolatedfromC(注：一种中草药),wastestedforantiviralactivityagainstvirusB.BothinvitroandinvivoassaysalongwithserumpharmacologicalexperimentsshowedAtohavepotentantiviralactivity.ThepharmacokineticprofileofAinSprague/DawleyratplasmaafteroraladministrationwasmeasuredbyHPLC.Bloodsamplestakenatselectedtimepointswereanalyzedtostudypotentialchangesinantiviralpharmacodynamicsasmeasuredbyinfectivityofviruses.FromthesimilarityoftheserumconcentrationprofilesandantiviralactivityprofilesitisconcludedthatAitself,ratherthanametabolite,exertedtheeffectagainsttheviruspriortobioinactivation.TheneedforeffectiveclinicalagentsagainstvirusBandtheseresultssuggestthepossibilityofbenefitfromfurtherexperimentswithA.Theauthorsshouldchecktobesurethatthetermsbloodsamples,plasmaandserumarealwaysusedappropriatelythroughouttheabstractandtext.Introduction:somesentencescanbemadelesspassive.example1stparagraphAappearstobethemostimportantalkaloidisolatedfromtheplant,itsstructuralformulaisshowninFig1....Whileitproducedageneralinhibitionofantibodyproductionlymphocyteproliferationwasstimulated(XiaandWang,1997).ThesepharmacologicalpropertiessuggestapotentialuseinthetreatmentofviralmyocarditisagainstvirusBthatcouldbestudiedinexperimentsincellcultureandanimals.Theauthorsshouldchecktheentiremanuscriptforspellingerrors(examplegiven:inyourtextalkaloidisincorrectlyspelledalkaloid)Theauthorsshouldreadtheguidelinestotheauthorsandnotincludethefirstnameoftheauthorsbeingcitedinthetext.Inthereferencesectionthefirstnameshouldbeabbreviatedasshownintheguidelinetoauthors(thustheearliertextreferenceshouldbe(Liuetal.,2003)andtheremainingoneshouldbe(Chenetal.,2002)Theauthorsinsteadofdirectlyansweringthefirstcomplexquestionofreviewer#1mayincludethethreequestionsasfutureresearchaiminthediscussionsection.Ratherthanredrawingfiguretheauthorsmaychoosetoamendthewordingofthestatisticalanalysissectiontostatethattheresultoftablesaremeans+-SEMandforfiguresare+-SD.reviewer#1commentnumber8andreviewer#2comment3mightbesatisfiedbyinclusionofarepresentativephotoofcellsandheartshowingCPE.Remembermostreadersofthejournalhaveneverseenwhatyouaretryingtodescribe.BecauseIthinkthatyoucandealwithallofthepointsraisedIamhopingtoseearevisedmanuscriptthatyouhavecarefullycheckedforerrors.IfyouhavequestionsordonotknowhowtorespondtoanyofthepointsraisedpleasecontactmeatJosephBahl,PhDEditor2LifeSciences作者回复信原稿：DearDr.Bahl,I’m（注：正式信函不要简写）veryappreciate（注：不适合作为给编辑回信的开始，同时有语法错误）foryourcommentsandsuggestions.I（注：实际上是学生做的）haveconductedinvivoantivirusexperimentsagain（注：要表明是应审稿人或编辑建议而作）.Miceweresacrificedon15daysand30daysafterinfection.Deathrate,heartweighttobodyweightratio(HW/BW),virustitersandpathologicslices（注：用词错误）werecalculated（注：用词不当）.ProductionofmRNAofIL-10,IFN-γandTNF-αwere（注：语法错误）measuredbyRT-PCR.Ihaverevisedthismanuscriptandespeciallypaidmuchattentiontoyourcommentsandsuggestions.Iwouldliketore-submitittoLIFESCIENCE.Titleofmanuscripthasbeenchangedto“TheantiviruseffectsofAagainstvirusBanditspharmacokineticbehaviourinSDratsserum”tomakeitmoreclearandsmooth.AnswerstoReviewers’questionswereasfollows:（注：可附在给编辑的回复信后）Reviewer#1:XXXXXReviewer#2:XXXXXEditorsnoteandsuggestions:Title:Re-writethetitletoreadmoresmoothlyincontemporaryEnglishAnswer:Ihaverewritethetitleto“TheantiviruseffectsofAagainstvirusBanditspharmacokineticbehaviourinSDratsserum”tomakeitmoreclearandsmooth（注：多处语法错误）.Abstract:Re-writetheabstracttoreadmoresmoothly.Answer:Ihaverevisetheabstractcarefullytomakeitmoresmooth