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英文论文投稿信Coverletter模板Case1DearEditor,WewouldliketosubmittheenclosedmanuscriptentitledGDNFAcutelyModulatesNeuronalExcitabilityandA-typePotassiumChannelsinMidbrainDopaminergicNeurons,whichwewishtobeconsideredforpublicationinNatureNeuroscience.GDNFhaslongbeenthoughttobeapotentneurotrophicfactorforthesurvivalofmidbraindopaminergicneurons,whicharedegeneratedinParkinson’sdisease.Inthispaper,wereportanunexpected,acuteeffectofGDNFonA-typepotassiumchannels,leadingtoapotentiationofneuronalexcitability,inthedopaminergicneuronsincultureaswellasinadultbrainslices.Further,weshowthatGDNFregulatestheK+channelsthroughamechanismthatinvolvesactivationofMAPkinase.Thus,thisstudyhasrevealed,forthefirsttime,anacutemodulationofionchannelsbyGDNF.OurfindingschallengetheclassicviewofGDNFasalong-termsurvivalfactorformidbraindopaminergicneurons,andsuggestthatthenormalfunctionofGDNFistoregulateneuronalexcitability,andconsequentlydopaminerelease.TheseresultsmayalsohaveimplicationsinthetreatmentofParkinson’sdisease.Duetoadirectcompetitionandconflictofinterest,werequestthatDrs.XXXofHarvardUniv.,andYYofYaleUniv.notbeconsideredasreviewers.Withthanksforyourconsideration,IamSincerelyyours,case2DearEditor,WewouldliketosubmittheenclosedmanuscriptentitledCa2+-bindingproteinfrequeninmediatesGDNF-inducedpotentiationofCa2+channelsandtransmitterrelease,whichwewishtobeconsideredforpublicationinNeuron.WebelievethattwoaspectsofthismanuscriptwillmakeitinterestingtogeneralreadersofNeuron.First,wereportthatGDNFhasalong-termregulatoryeffectonneurotransmitterreleaseattheneuromuscularsynapses.Thisprovidesthefirstphysiologicalevidenceforaroleofthisnewfamilyofneurotrophicfactorsinfunctionalsynaptictransmission.Second,weshowthattheGDNFeffectismediatedbyenhancingtheexpressionoftheCa2+-bindingproteinfrequenin.Further,GDNFandfrequeninfacilitatesynaptictransmissionbyenhancingCa2+channelactivity,leadingtoanenhancementofCa2+influx.Thus,thisstudyhasidentified,forthefirsttime,amoleculartargetthatmediatesthelong-term,synapticactionofaneurotrophicfactor.Ourfindingsmayalsohavegeneralimplicationsinthecellbiologyofneurotransmitterrelease.[0630][投稿写作]某杂志给出的标准SampleCoverLetter[theexampleusedistheIJEB]Case3SampleCoverLetter[theexampleusedistheIJEB]DearEditorofthe[pleasetypeinjournaltitleoracronym]:Enclosedisapaper,entitledMobileAgentsforNetworkManagement.Pleaseacceptitasacandidateforpublicationinthe[journaltitle].Belowareourresponsestoyoursubmissionrequirements.1.Titleandthecentralthemeofthearticle.Papertitle:MobileAgentsforNetworkManagement.Thisstudyreviewstheconceptsofmobileagentsanddistributednetworkmanagementsystem.Itproposesamobileagent-basedimplementationframeworkandcreatesaprototypesystemtodemonstratethesuperiorperformanceofamobileagent-basednetworkovertheconventionalclient-serverarchitectureinalargenetworkenvironment.2.Whichsubject/themeoftheJournalthematerialfitsNewenablingtechnologies(ifnomatchingsubject/theme,enter'Subjecthighlyrelatedto[subjectofjournal]butnotlistedby[pleasetypeinjournaltitleoracronym])3.Whythematerialisimportantinitsfieldandwhythematerialshouldbepublishedin[pleasetypeinjournaltitleoracronym]?Thenecessityofhavinganeffectivecomputernetworkisrapidlygrowingalongsidetheimplementationofinformationtechnology.Findinganappropriatenetworkmanagementsystemhasbecomeincreasinglyimportanttoday'sdistributedenvironment.However,theconventionalcentralizedarchitecture,whichroutinelyrequeststhestatusinformationoflocalunitsbythecentralserver,isnotsufficienttomanagethegrowingrequests.Recently,anewframeworkthatusesmobileagenttechnologytoassistthedistributedmanagementhasemerged.Themobileagentreducesnetworktraffic,distributesmanagementtasks,andimprovesoperationalperformance.Giventoday'sbandwidthdemandovertheInternet,itisimportantforthe[journaltitle/acronym]readerstounderstandthistechnologyanditsbenefits.Thisstudygivesareal-lifeexampleofhowtousemobileagentsfordistributednetworkmanagement.Itisthefirstintheliteraturethatreportstheanalysisofnetworkperformancebasedonanoperationalprototypeofmobileagent-baseddistributednetwork.Westronglybelievethecontributionofthisstudywarrantsitspublicationinthe[journaltitle/acronym].4.Names,addresses,andemailaddressesoffourexpertreferees.Prof.Dr.WilliamGatesChairProfessorofInformationTechnology321JohnsonHallPremierUniversityLancaster,NY00012-6666,USAphone:+1-888-888-8888-fax:+1-888-888-8886e-mail:Expertise:publishedarelatedpaper(TCP/IPandOSI:FourStrategiesforInterconnection)inCACM,38(3),pp.188-198.Relationship:ImetDr.Gateonlyonceataconferencein1999.Ididn'tknowhimpersonally.AssocProf.Dr.JohnAdamsDirectorofNetworkResearchCenterCollegeofBusinessAustralianUniversity123,HarborDriveSydney,Australia56789phone:+61-8-8888-8888-fax:+61-8-8888-8886e-mail:Expertise:publishedarelatedpaper(CreatingMobileAgents)inIEEETOSE,18(8),pp.88-98.Relationship:None.IhavenevermetDr.Adams.AssocProf.Dr.Chia-HoChenChairofMISDepartmentCollegeofManagementOpenUniversity888,PutongRoadKeelung,Taiwan100phone:+886-2-8888-8888-fax:+886-2-8888-8886e-mail:Expertise:publishedarelatedpap