1山东中医药大学研究生试题姓名年级学号所属学院学位层次博士/硕士类别统招/在职课程名称医学统计学授课教师考试时间2014.12.29考试成绩四、计算分析题1(本题10分)2013年随机抽取某地102名成年男子测量其血红蛋白含量(g/L)的资料如下,109103143118137158118148121149147145138130125138121135152130151131135141145140111124144122136153129150146146145140142116128138123133157124140135143142173151115129141119131152127141133131133150132113128143126132155120139153160162145144117134142132135156130142129127137138161117133139137131154125147150147148试制定该地成年男子血红蛋白含量95%的参考值范围。五、计算分析题2(本题10分)某研究者为比较耳垂血和手指血的白细胞数,调查9名成年人,同时采取耳垂血和手指血见下表,试比较两者的白细胞数有无不同?9名成人耳垂血和手指血白细胞数(109个/L)比较编号123456789耳垂血9.76.67.05.38.49.84.95.67.9手指血6.95.45.75.07.58.34.54.17.5六、计算分析题3(本题12分)探讨柴胡-黄芩水煎液中分离出的4类主要化学成分群的不同配伍与解热作用的相关性。选用L8(27)正交设计模型,柴胡-黄芩水煎液中分离出的4类主要化学成分群分别为:挥发油(A)、多糖(B)、皂苷(C)、黄酮(D),同时研究挥发油(A)与多糖(B)的交互作用。方法:LPS(脂多糖)诱导的发热模型大鼠,根据实验方案,分别接受不同的成分群配伍,观察大鼠体温下降值,结果如下表。试对此资料进行方差分析。2实验号表头和列号实验方案实验结果Y1234567ABA×BCD11111111A1B1C1D12.0921112222A1B1C2D22.1431221122A1B2C1D21.5441222211A1B2C2D11.4352121212A2B1C1D20.8162122121A2B1C2D10.7272211221A2B2C1D10.6182212112A2B2C2D20.72七、计算分析题4(本题13分)某医院将150例慢性乙型肝炎病人随机分为三组,分别用苦参素、干扰素和常规保肝治疗6个月,HBeAg转阴率的观察结果如下表,试比较三组疗效有无差别?三组疗效比较组别有效人数无效人数合计苦参素组173350干扰素组262450常规护肝组44050合计47103150八、计算分析题5(本题10分)某医生采用复方猪胆胶囊对治疗两种病情的慢性支气管炎病人的疗效进行比较,所得结果见下表,试比较两组差别有无统计学意义?两种病情的慢性支气管炎病人的疗效组别疗效(例数)治愈显效好转无效喘息型23836511单纯型60985112九、计算分析题6(本题15分)某研究者探索老年男性冠心病患者中血清总胆固醇(Y)与低密度脂蛋白(1X)、高密度脂蛋白(2X)、甘油三酯(3X)、体质指数(4X)间的线性关系,为冠心病的诊断与治疗提供更有意义的预测指标。测量了50名老年男性冠心病患者的血清总胆固醇、低密度脂蛋白、高密度脂蛋白、甘油三酯和体质指数,资料如下表,试对男性冠心病患者血清总胆固醇与低密度脂蛋白、高密度脂蛋白、甘油三酯、体质指数进行回归分析,并对367.21X、83.12X、59.13X、80.264X时总体血清总胆固醇进行预测。。50名老年男性冠心病患者血清学指标及体质指数的测量结果序号id低密度脂蛋白(mmol/L)高密度脂蛋白(mmol/L)甘油三酯(mmol/L)体质指数(Kg/m2)总胆固醇(mmol/L)1X2X3X4XY11.251.621.4721.803.4822.261.211.3922.203.4432.831.641.5622.804.8743.221.101.5921.804.6153.521.712.2528.105.4561.831.921.4729.603.9772.441.251.4320.303.8383.822.101.8723.706.2592.451.631.3326.004.18103.361.921.6733.405.73112.941.840.7420.704.31123.101.451.3421.604.82133.851.441.7626.506.03142.261.531.0225.503.88153.571.591.6627.105.28162.811.521.5425.004.56173.511.182.1527.205.22182.191.411.6825.104.27192.551.241.8925.004.47201.421.751.7024.203.52213.641.992.1528.205.42222.881.321.4521.604.25232.851.271.6328.004.16242.881.151.6430.704.33253.171.381.2926.404.61263.872.162.6324.906.15272.652.140.7220.104.84284.181.901.6628.606.49293.491.271.6726.005.52303.161.831.5034.205.16312.852.301.7820.005.57322.941.521.6926.404.51333.422.251.3819.405.674343.281.711.3026.105.14353.161.451.7423.704.69362.861.421.6728.604.21373.151.581.3127.604.63383.391.521.3526.205.19393.111.251.7030.804.58401.782.270.7024.004.01412.931.831.3626.003.99421.842.381.5225.404.45434.391.681.8325.106.17443.371.462.2526.105.72451.712.250.7316.803.88463.251.382.3430.105.16472.801.572.1127.104.92482.142.041.3928.904.31492.332.020.9120.204.63502.651.091.9428.104.46