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ImagingdiagnosisofthyroidcarcinomaZHANGJingJIANGYu-xinDepartmentofDiagnosticUltrasoundPekingUnionMedicalCollegeHospitalChineseAcademyofMedicalScienceBeijing100730ChinaAbstractNoninvasiveimagingofthyroidcarcinomaincludeultrsonographyradioisotopeimagingcomputedtomographymagnet-icresonanceimaging.UltrasonographyThyroidcarcinomamanifestsasahypoechonodulewithirregularcontourill-definedmarginmicrocalcificationwithouthalo.Invasionofadjacenttissueorlymphnodemetastasisarecommon.OncolorDopplerflowimagingin-tranodularbloodflowisvaluable.RadioisotopeimagingThecommonlyuseddrugare99Tcmand131I.Malignantlesionsareoftencoldnodule.Indynamicimagingtheyareseenat14-18sandthepeakisat16s.MagneticresonanceimagingOnT1-weightedimagethesignalofmalignantlesionissimilarwithnormalthyroidonT2-weightedimagethesignalishighintensity.Conventionalimagingcannotdifferentiatemalignantfrombenign.Nowwith67Gaenhancingthisconditionmightbeimproved.Computedtomo-graphyItisalwaysusedtodefinethescaleofthetumorandthemetastasisoflymphnode.Themalignantlesioncanbelowdensitywithirregularshapeandill-definedmargin.Enlargedlymphnodesarecommon.KeywordsThyroidcarcinomaUltrasonographyRadioisotopeimagingTomographyX-raycomputedMagneticresonanceim-aging10073099Tcm131I14～18s16s50%～75%T1T267GaXR736.1R445A1003-3289200402-0308-031974-2003-08-21USCTMRI12～3mm27%～33%121.1①②+1100µm1100µmKakkos5404③④⑤1⑥Wunderbaldinger128032004202ChinJMedImagingTechnol2004Vol20No2⑦11.2Rago3ⅠⅡⅢⅢ16Rago310466.6%77%75.6%66%93.2%Ⅲ97.2%Koike4309329FNABUS-FNABTollin6MNGUS-FNAB1cm1cm/112γ-ECTECTSPECTECTPET131I99Tcm201Tl99Tcm131I131I123I131I99Tcm-MIBI99Tcm-15HSPECT131I99Tcm-4O14%～22%14～18s16s7Sinha7201Tl3h131I201TlCl131CsClPETPlotkin818Fluor-2-Deoxyglucose-PET18F-FDG-PET18F-FDG-PET92%80%173CT3.1143.250%～75%8.3%5mm15mmCTCT13144MRIT1T2T1T28mmT23/467Ga679032004202ChinJMedImagingTechnol2004Vol20No2GaMRI①T1T2T1-T2②③④T1⑤45～90s200%9101JamesCStarksMMacGillivrayDCetal.Theuseofimagingstudiesinthediagnosisandmanagementofthyroidcancerandhyper-parathyroidismJ.SurgOncolClinNAm199981145-169.2GallowayRJSmallridgeRC.Imaginginthy-roidcancerJ.EndocrinologyandMetabo-lismClinicsofNorthAmerica199625193-113.3RagoTVittiPChovatoLetal.RoleofconventionalultrasonographyandcolorflowDopplersonographyinpredictingmalignancyincoldthyroidnodulesJ.EuropeanJournalofEndocrinology1998138141-46.4KoikeENoguchiSYamashitaHetal.Ul-trasonographiccharacteristicsofthyroidnod-ulesJ.ArchSurg20011363334-337.5KakkosSKScopaCDChalmoukisAKetal.RelativeriskofcancerinsonographicallydetectedthyroidnoduleswithcalcificationsJ.JournalofClinicalUltrsound2000287347-352.6TollinSRMeryGMJelvehNetal.Theuseoffine-needleaaspirationbiopsyunderultra-soundguidancetoassesstheriskofmalig-nancyinpatientswithamultinodulargoiterJ.Thyroid2000103235-241.7SinhaPSBeebyDIRyanP.AnevaluationofthalliumimagingfordetectionofcarcinomainclincallypalpablesolitarynonfunctioningthyroidnodulesJ.Thyroid200111185-89.8PlotkinMHautzelHKrauseBJetal.Im-plicationof2-18Fluor-2-Deoxyglucoseposi-tronemissiontomographyinthefollow-upofHürthlecellthyroidcancerJ.Thyroid2002122155-161.9NakaharaHNoguchiSMurakamiNetal.Gadolinium-enhancedMRimagingofthyroidandparathyroidmassesJ.Radiology19972023765-772.10TakashimaSMatsushitaTTakayamaFetal.Prognosticsignificanceofmagneticresnancefindingsinadvancedpapillarythy-roidcancerJ.Thyroid200111121153-1159.11HatipogluBAGierlowskiTShore-Freed-manEetal.Fine-needleaspirationofthy-roidnodulesinradiation-exposedpatientsJ.Thyroid200010163-68.12WunderbaldingerPHarisinghaniMGHahnPFetal.CysticlymphnodemetastasesinpapillarythyroidcarcinomaJ.AmericanJournalofRoentgenography20021782693-697.13LuoDHShiMLLiF.CTmanifestationoflymphnodemetastasisofthyroidcarcinomaJ.ChinJRadiol200236136..CTJ.200236136.14ChenQYWuYQYangSetal.Compari-sonstudyofCTandphysicalpalpationindiagnosisofthyroidcarcinomaJ.JChinClinMedImaging2001123158..CTJ.2001123158.15PanKWuYJiaSWetal.Analysisofim-ageexaminationfordiagnosisandoperativetreatmentofthyroidcancerJ.ChinJMedImagingTechnol200016264..J.2000168641-642.16ZhaiXLZhangJGGuoLL.ComparisionofcolorDopplerultrasoundandpathologyofthyroidnodulesJ.ChinJUltrasonogr200096382..J.200096382.17LiuLF.PETfunctionalimagingdetecttumorofheadandneckJ.ChinJMedImaging200195363..J.200195363.0132004202ChinJMedImagingTechnol2004Vol20No2