中国鼻咽癌流行概况-梁锌

，，，，，（/，100021）：（IARC），、，，。，38.29%40.14%，（1.2/10，0.7/10），1823，。，，（65）。，，，，，。：；；；：R739.63；R73-31：A：1004-0242（2016）11-0835-06doi：10.11735/j.issn.1004-0242.2016.11.A001NasopharynxCancerEpidemiologyinChinaLIANGXin，YANGJian，GAOTing，etal.（NationalCancerCenter/CancerHospital，ChineseAcademyofMedicalSciencesandPekingU-nionMedicalCollege，Beijing100021，China）Abstract：AnalysisandcomparisonofthenasopharynxcancerburdeninChinaandotherregionsoftheworldwithusingincidenceandmortalityrates，whichobtainfromtheglobalcancerdatabasepublishedbytheInternationalAgencyforResearchonCancer(IARC).Itwasfoundthatbothna-sopharynxcancerincidenceandmortalityinChinaaccountfor38.29%and40.14%ofglobalna-sopharynxcancer，respectively，withahighlevelofincidenceandmortality(1.9/105and1.2/105)，whichrankedas18and23intheword，respectively.Incidenceandmortalityofnasopharynxcan-cerarehigherformalethanforfemale.ThenumberofnewcasesofnasopharynxcancerinChinaisrelativelylargeintheyoungandmiddleaged，andthenumberofdeathsisrelativelylargeinthemiddle-agedandaged，buttheincidenceandmortalityofnasopharynxcancerarebothrelativelyhighinoldgroupover65yearsofage.TheburdenofnasopharynxisrelativelylargeinChina，witharelativelybadprognosisandalowlevelofsurvivalrate，andthissuggestedthatthescreen-ingshouldstartactivelyamongthehighriskgroupofnasopharynxcancer，especiallyinGuang-dongandGuangxiprovinceinChina.Keywords：nasopharynxcancer；incidence；mortality；China：2016-02-01；：2016-04-19：（3332015087）；（LC2014B07）：，E-mail：[e-mail]［1~4］，（、），［5~7］。［8］，20，45~60［7，9］。、EB［5，10］，［11］。，、，，。，，。11.1（IARC）/835（1/105）ASR（1/105）RankNumbersCruderate（1/105）ASR（1/105）RankWorld866911.21.2-508310.70.7-Moredevelopedregions71670.60.4-33760.30.2-Lessdevelopedregions795241.41.4-474550.80.9-Asia701081.61.6-414141.00.9-South-EasternAsia255964.24.3-141732.32.5-Micronesia142.62.7-50.91.2-EasternAsia364202.31.8-220171.41.0-China331982.41.918204041.51.226Japan5530.40.21283240.30.1119Korea,Republicof4420.90.7611850.40.377Malaysia20306.97.216982.42.54Singapore4739.06.422184.12.83Indonesia130845.35.6373913.03.32VietNam49315.55.4428853.23.31Brunei153.65.0561.52.15Canada2480.70.578950.30.299UnitedStatesofAmerica20300.60.5807550.20.2109RussianFederation4560.30.21343800.30.2100Denmark240.40.3116100.20.1121Norway130.30.213630.10156UnitedKingdom3090.50.4961170.20.1124Italy4390.70.5771900.30.297France(metropolitan)3010.50.31121270.20.1127Germany4480.50.31091600.20.1129NewZealand320.70.669150.30.291（IACR）（Globocan2012：http：//globocan.iarc.fr/）。、、，、。，，，Globo-can2012。1.2，、、（）、。Segi’s，（age-standardizedrate，ASR）。，、，。22.18，（1.4/10），（4.3/10）、（1.8/10），（0.4/10），3.5。（1.9/10）（1.2/10），18，19.29%38.29%。（7.2/10）、（6.4/10）、（5.6/10）、（5.4/10）、（5.0/10）5，61，128，。，82.32%91.73%，17.66%，8.27%，（1.11）（0.47）2.36。Table1，Table2。2.2，，。，0～39，40，ASR：Age-standardizedratebyworldstandardpopulation.Table1IncidenceandmortalityofNasopharynxcancerinChinacomparedtootherregions836～；，，39，40，75。，，，。，。Figure1，Figure2。2.35，（0.9/10）（0.2/10），4.5。（2.5/10）、（1.2/10）、（1.0/10），（3.3/10）、（3.3/10）、（2.8/10）、（2.5/10）、（2.1/10）5。，。（1.2/10）（0.7/10），23，19.29%40.14%。82.32%93.36%，17.66%，6.64%，（1.13）（0.38）2.97。/，（1.00）（0.75），（0.63），。Table1，Table2，Figure3。2.4，，。，0～39，40，75；，，0～39，40，75。，，，。，。Figure3，Figure4。Table2IndexfornasopharynxcancerburdeninChinacomparedtootherregionsNote：I/P：incidenceratiotopopulationratio，D/P：deathratiotopopulationratio，M/I：mortalitytoincidenceratio.83720162511ChinaCancer,2016,Vol.25,No.11Figure2Age-specificincidenceandnumberofcasesfornasopharynxcancerinChina0~15~40~45~50~55~60~65~70~75+Age(years)MalecasesFemalecasesMaleincidenceFemaleincidence1284040003500300025002000150010005000Incidence(1/105)NumberofcasesFigure3Age-specificmortalityofnasopharynxcancerindifferentregions128400~15~40~45~50~55~60~65~70~75+Female128400~15~40~45~50~55~60~65~70~75+MaleMortality(1/105)ChinaMoredevelopedLessdevelopedWorldFigure1Age-specificincidenceofnasopharynxcancerindifferentregions128400~15~40~45~50~55~60~65~70~75+Female128400~15~40~45~50~55~60~65~70~75+