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:,,100095,,,,,,,,,,,X20%11,21(),31:(Poncet)41(PPD2C5TU):,,,(),,51,,,XX,,X:112131X(),41516171()3cm,,81()CT:11,213141,516111::(BALF),,,2,0720012242ChinJTubercRespirDis,February2001,Vol24,No.2,,,,3,,,,4872hBACTEC,BACTEC10%,,21:36,,,11(g/ml)(g/ml)(INH,H)1011(SM,S)1001010(PAS,P)1011(EMB,E)5055(RFP,R)2505050(TB1)100101(1321TH,PTH,TH)1002525(KM)1001010(CPM)1001010(CS)402020:INH1RFP50SM20EMB5KM100CPM1001321TH25PAS1CS40g/ml,INH011EMB215g/ml;PZABACTEC,C14,,,,31BALF(PCR)+:,,PCRPCRDNA,,PCR+,,,41:,,,:,:11X213141PPD(5TU);51PCR+6171BALF81163781X,,,11(),,,,,21,,X,,,311720012242ChinJTubercRespirDis,February2001,Vol24,No.2,X()41,,PPD(-)51X,,,,,61,,,,(1999)11:,21:()31:,41:51:,,,()11:,,,,,510U25%40ml,1015min1020U5%500ml1020mg25%40ml,1015min1020mg5%250ml(),,21::;;,,,20%,2,1,:-10-14cmH2O(1cmH2O=01098kPa)31:(),,,,G2,(),,,X,,,,:2720012242ChinJTubercRespirDis,February2001,Vol24,No.2,,,(directlyobservedtreatmentshort2course,DOTS),,,,()(MDR2TB),,11:::;;1:2/4,:2S(E)HRZ/4HR;2S(E)HRZ/4H3R3;2S3(E3)H3R3Z3/4H3R3;2S(E)HRZ/4HRE;2RIFATER/4RIFINAH(RIFATER:,RIFINAH:)2,1,6(1)5,6,2,8(),,3,HR69,91221:::;;1;:3/5:2SHRZE/1HRZE/5HRE;2SHRZE/1HRZE/5H3R3E3;2S3H3R3Z3E3/1H3R3Z3E3/5H3R3E3,,,31:INHRFPMDR2TB,:,21,WHOMDR2TB,INHRFP,:SM:,2,EMB,SM,SMPZA:,,PZA(),MDR2TBEMB:SM,,(AMK):(1314TH):(OFLX)(LVFX),PZA,:,:,(RBT):RFP(,PSNZ):,INH,,MDR2TBWHO()MDR2TB,AMK(CPM)+TH+PZA+OFLX,TH+OFLX3,18,21,,3,4,23,,2,33720012242ChinJTubercRespirDis,February2001,Vol24,No.22(g)50kg50kg(mg/kg)(g)50kg50kg33(INHH)01301310150150161(SMS)017501751530017501751(RFPR)0145016102001601612h(RFTL)0145301631,(PZAZ)1151152030210210123(EMBE)017511015251101121(PTHTH)017511010203(PASP)81081015025010123(AMK)01401410200140141(CPM)01750175017501751(OFLXO)014016123(LVFXV)013013123(PSNZ)01601923:32,333(mg)()(,RIFATER)R120,H80,Z250250kg460kg51,(,RIFINAH)R150,H100431,:,,,,,,:11:,,,,,,,21:,,,31:,,,(:2000207231)(:)4720012242ChinJTubercRespirDis,February2001,Vol24,No.2