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10119972JournalofIsotopesVol.10No.1Feb.1997CEASFB2-MGRIA(,450003)(RIA)109(353242)30CEASFB22MG,20,CEASFB22MG(P0.01),56.9%72.5%47.7%,CEASFB22MG91.7%B22MG(P0.05),CEASF(P0.01),B22(),,[1],(CEA)(SF)B22(B22MG)CEASFB22MG,,,,19911-19951109CEASFB22MGRIA11.1(1):30,18,12,20-43,,(2):109,21-70,54,1981WHO,3532421.22mL,,201-2:1995212211:1996201222©1994-2006ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.(1):CEA11.393.20LgöL,15LgöL;SF132.7688.45LgöL,240LgöL;B22MG1.660.85mgöL,2.6mgöL(2):CEASFB22MG(1),,CEA(P0.05),(P0.01)10912,CEA9,5CEA80LgöL;B22MG6;SF5,4SF500LgöL1CEASFB2-MG(xqs)CEAöLgL-1ö%SFöLgL-1ö%B22MGömgL-1ö%3011.393.20132.7688.451.660.8510922.3017.661)56.9370.28159.901)72.53.071.411)47.73525.8720.501)57.1350.50171.231)65.73.031.321)57.03221.1014.912)59.4380.84160.671)78.13.291.591)46.94220.2516.992)54.8378.76151.731)73.82.931.371)40.5:,1)P0.01;2)P0.0520,CEASFB22MG15.344.24LgöL156.4879.62LgöL2.981.13mgöL;24.1615.34LgöL369.46148.34LgöL2.961.32mgöL,B22MG(P0.05),CEASF(P0.01)(3)CEASFB22MG22,2CEASFB2-MGCEA+SFö%CEA+B22MGö%SF+B22MGö%CEA+SF+B22MGö%1099082.68174.39587.210091.7352777.12982.92880.03291.4322887.52371.82990.62990.6423583.32969.03890.53992.0141:CEASFB22MGRIA©1994-2006ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.(HenanTumourHospital,Zhengzhou450003)ABSTRACTThecontentsoftheserumCEA,SFandB22MGfor109casesoflungcancer(35adenocar2cinomacases,32squamouscellcarcinomacasesand42smallcellcarcinomacases)and30nor2malcontrolsaredeterminedbyRIA.Thepre2andpost2chemotherapeuticchangesareobservedfor20casesoflungcancer.TheresultsshowthatthevalueofserumCEA,SFandB22MGofthe109casesisclearlyoverthatofthenormalcontrols(P0.01)withthepositiveratesbeing56.9%,72.5%and47.7%,respectively.Thepositiverateofthecombiningassaycanbeashighas91.7%.Thepost2chemotherapeuticB22MGcontentofpatientswithlungcancershowsnoapparentdecline(P0.05).However,theirserumCEAandSFdeclinesharply(P0.01).TheabovestudiesrevealthatthecombinedRIAisofsignificantclinicalvalueinthediagnosisoflungcancer.Keywordscarcino2embryonicantigen(CEA)serumferritin(SF)B22microglobulin(B22MG)radioimmunoassay(RIA)lungcancer341:CEASFB22MGRIA©1994-2006ChinaAcademicJournalElectronicPublishingHouse.Allrightsreserved.