30120112ChineseJournalofBiomedicalEngineeringVol.30No.1February2011doi10.3969/j.issn.0258-8021.2011.01.0232010-03-172010-11-1910074043*。E-mailyanbige@163.com*710062。MATLABPDE。x。R318D0258-8021201101-0140-06SimulationoftheApplicationofUltrasoundElastographyinBreastDiseaseDiagnosisZHAOTing-TingYANBi-Ge*CollegeofPhysicsandInformationTechnologyShanxiNormalUniversityXi'an710062ChinaKeywordsbreasttumorsultrasounicelastographystrain。1。。。。、2。。、。。。1MatlabPDE。1.6cm×1.6cm0.1cm。ν0.495。2%。Dirichletx0.02PDEr10.02xr10Neumann。2%。17∶15∶12∶1x。。。。。。7∶15∶12∶1x。。3-4。5。。。62~3。4.50kg/L1.50kg/L。22.1x12。。1-0.1≤x≤0.1x。2-0.1≤x≤0.1。-0.4≤x≤0.4。1x。a7∶1b5∶1c2∶1Fig.1StraindistributionofcirculartumorinxdirectionfordifferentYoung'smodulusratio.a7∶1b5∶1c2∶134。3x4。3-0.1≤x≤0.1x1141302。a7∶1b5∶1c2∶1Fig.2shearstraindistributionofcirculartumorfordifferentYoung'smodulusratio.a7∶1b5∶1c2∶1。4-0.1≤x≤0.1。-0.4≤x≤0.4。3x。a7∶1b5∶1c2∶1Fig.3StraindistributionofstartumorinXdirectionfordifferentYoungsmodulusratio.a7∶1b5∶1c2∶12.2x56。5ab-0.1≤x≤0.1x。6ab-0.1≤x≤0.1x24114。a7∶1b5∶1c2∶1Fig.4ShearstraindistributionofstartumorfordifferentYoung'smodulusratio.a7∶1b5∶1c2∶1。56。3x1。15。axbFig.5Strainfigureofstartumor.axdirectionofstrainbshearstrainxx7。。341306。axbFig.6Strainfigureofcircletumor.axdirectionofstrainbshearstrain。1Tab.1StraincomparisonofdifferenttumorshapswiththesameYoung’smodulusx7∶15∶12∶1x2。2Tab.2StraincomparisonwiththesameYoung’smodulusofdifferentdensitytumorx2∶12x。、。。、。6225、84.00%96.77%93.10%8。。4、x。。。1.M..2006137-160.2.J.1999157503.44113KrouskopTAWheelerTMKallelFetal.ElasticmoduliofbreastandprostatetissueundercompressionJ.UltrasonicImaging1998204260-274.4KhalilASRaymondCCAlexandraHCetal.TissueelasticityestimationwithopticalcoherenceelastographytowardmechanicalcharacterizationofinvivosofttissueJ.AnnBiomedEng200533111631-1639.5HanLNobleJABurcherM.AnovelultrasoundindentationsystemformeasuringbiomechanicalpropertiesofinvivosofttissueJ.UltrasoundMedBiol2003296813-823.6.J.200612155-57.7KallelFBertrandMOphirJ.FundamentallimitationsonthecontrasttransferefficiencyinelastographyananalyticstudyJ.UltrasouninMed&Biol1996224463-470.8.J.201026101902.541