GRADEprofiler软件的使用简介

20111235ChinJEvidBasedCardiovascMedDecember2011Vol．3No．5··GRADEprofilerR4A1674-4055201105-0390-031。。GRADE、GradesofRecommendationsAssessmentDevelopmentandEval-uationGRADE2004--GRADE2-3。、、GRADE、GRADEproGRADEprofilersoft-ware43．6。GRADEpro3．6。1GRADEproGRADEpro3．6http//ims．cochrane．org/revman/oth-er-resources/gradepro/download。“C\ProgramFiles\GRADEprofiler”。。GRADEpro2．0Microsoft．NETFrameworkversion2．0。2GRADEproGRADEpro。。GRADE。ProfilestreeEdit。。3GRADEproGRADEpro4CochraneCDSRtheSummaryofFindingstableSoFGRADEGRADEevidenceprofileEPOverviewofReviewstableOoR。GRADEGRADEproCochrane。、、[e-mail]10．3969/j．issn．1674-4055．2011．05．023。SoF、EPOoR/MetaSR/MAGRADE。GRADEproGRADEproSoFRevMan5RevMan5．1TablesSummaryoffindingstables。4GRADEpro《Meta》“T”4GRADEpro3．6。GRADEpro3．6“help”。4．1GRADEGradedatafileGRADEpro3．6“File”“New”“T”“”“．grd”GRADE。4．2“ProfileGroupname”SR/MA“T”“Addprofile”“Evi-denceprofile”“Profileinformation”。4．3SR/MASR/MA“Evidenceprofile”“Profileinformation”。“Evidenceprofile”“Format”“shouldinterventionvscompari-sionbeusedforhealthproblem”“Interven-tion、Comparsion、HealthproblemSetting”4“Format”“Inter-ventionSetting”2。SR/MA“Question”“SoFtitle”。“Timeframe”2007～2010。“Profileinformation”“Bibliography”SR/MA“T”“Profileauthors”“CreatedonLastmajorupdate”。①“SoFtitle”“Edit”。“Question”②“Setting”“”“Otherconsiderations”“、、”。4．44．3“Addoutcome”。“Nameofoutcome”“Shortname”“Importance”·093·20111235ChinJEvidBasedCardiovascMedDecember2011Vol．3No．55“IMPORTANCE”“Assessed/measuredwith”“”“Noofstud-ies”8“Studydesign”“Studydesign”randomisedtrails“Lengthoffollow-up”range38．3to98．7、“oth-er”min。3①1～3NOTIMPORTANT②4～6IMPORTANT③7～9CRITICAL。SR/MA。4．5。“Studyde-sign”randomisedstudies。“Downgradequalityofevi-dence”“Upgradequalityofevidence”“Footnote”“no”。GRADE1。①“Upgradequalityofevidence”“Publicationbias”“Otherconsid-erations”②GRADEpro3．6“Publicationbias”GRADEpro3．2“12”“1”。“no”“”“Qualityofevidence”“HIGH”“”“MORDERATE”“Otherconsiderations”“reportingbias”“Downgradequalityofevidence”“HIGH→MORDERATE→LOW”“Up-gradequalityofevidence”“LOW→MORDERATE→HIGH”。1GRADE4．6“GotoSummaryofFindings”。“Outcome”“”。“dichoto-mouscontinuous”continuous“pooled”pooled“totalnumberofpar-ticipants”“Intervention”470“Control”521“Interven-tionControl”“Finalvalues/changescoresincontrols”range38．3to98．7“Units”min“EstimateoftheEffect”SMD“of”SMD1．07“95%CI”SMD95%from0．19to1．94“Rangeofpossiblescores”0to4“Betterindicatedby”higher。“pooled”“notmeasured”“notreported”4．5。4．7EP、SoFOoR“View”。“PerviewSoFtable”。continuousdichotomous。4．84．8．1“Add”“Outcome”“”“Addoutcome”“Newoutcome”“”。4．4。4．8．24．4～4．7。“Newoutcome”“Nameofoutcome”“”。“GotoSummaryofFindings”“dichoto-mous”%。4．9SoF“PerviewSoFtable”。SoF“Selectformat”“GRADEevidenceprof”EP。“Options”“Exporttabletemplate”“No．ofrows”。4．10SoFSoF、EPOoR3。“SaveHTMLfile”EPHTML“SaveasImage”“Imageformat”“Quality”“ExporttoWordDocument”word。“SaveasImage”SoF、EPOoR“jpeg”4．1。5GRADEproRevMan·193·20111235ChinJEvidBasedCardiovascMedDecember2011Vol．3No．545GRADEpro3．6RevMan5．1。。5．1GRADEpro3．6RevManGRADEpro3．6“File”“Importfrom”“ReviewManagerfile”T．rm5“”“T．rm5”。“”“”4．4“NameofoutcomeNoofstudies”4．4。“GotoSummaryofFindings”4．5。“Finalvalues/changescoresincontrols、Units、Rangeofpossiblescores”3。4．7、4、94．10。“”4．8“GotoSummaryofFind-ings”。5．2RevMan5．1SoF44．7“File”“Exportas”“ReviewManagerSoF”“”“T”“”“T．SoF”。“T．rm5”RevMan5．1“Tables”“SummaryofFindingstables”“AddSummaryofFindingsTable”1。“NewSummaryofFindingsTableWizard”“Importtheta-blefromafliecreatedinGRADEprofiler”“CreatethetableusingRevMan＇stableeditor”3RevMan5SoF“Next”“Open”GRADEpro3．6“T．SoF”2“Open”“Finsh”SoFRev-Man5．13。1236GRADE。GRADE6。GRADEGRADEpro。GRADEGRADEproSR/MA。、GRADEGRADEGRADE。GRADEpro。GRADEpro3．6、3。GRADEpro3．2GRADEpro3．6v3．6、GRADE。GRADEproGRADEGRADEGRADEpro、。1WorldreportonknowledgeforbetterhealthstrengtheninghealthsystemsR．GenevaWorldHealthOrganization2004．2AtkinsDBestDBrissPAetal．GradingqualityofevidenceandstrengthofrecommendationsJ．BMJ200432874541490-1494．3．GRADEJ．2011119985-990．4GRADEpro．Computerprogram．Version3．2forWindows．JanBrozekAndrewOxmanHolgerSchünemann2008．5．MetaJ．201111101172-1183．6GuyattGHOxmanADVistGEetal．GRADEanemergingcon-sensusonratingqualityofevidenceandstrengthofrecommenda-tionsJ．BMJ20083367650924-926．2011-09-052011-10-21·293·