1.BriefintroductionofTuYouyou2.Malariaresearch-artemisinin3.Inspiration1Briefintroduction•TuYouyou,bornin1930inNingbo,hasbeenapharmacologistattheChinaAcademyofChineseMedicineSciencesince1965,engaginginresearchofthecombinationofTCMandWM.•TCM:traditionalChinesemedicine•WM:westernmedicine2•Herdiscoveryofartemisininanditstreatmentofmalariaisregardedasasignificantbreakthroughoftropicalmedicineinthe20thcenturyandhealthimprovementforpeopleoftropicaldevelopingcountriesinSouthAsia,Africa,andSouthAmerica.Forherwork,Tureceivedthe2011LaskerAwardinclinicalmedicineandthe2015NobelPrizeinPhysiologyorMedicine.3•In11December(BeijingTime),TuYouyoureceivedher2015NobelPrizeinPhysiologyorMedicineinSweden.4•TuisthefirstChineseNobellaureateinphysiologyormedicineandthefirstcitizenofthePeople'sRepublicofChinatoreceivetheNobelPrizeinnaturalsciences.•“TheProfessorofThreeNos”:nopostgraduatedegree,nostudyorresearchexperienceabroad,notamemberofanyChinesenationalacademies.5Malariaresearch-artemisinin•Artemisinin,adrugthathassignificantlyreducedthedeathrateofmalariapatients,andsavedmillionsoflivesacrosstheglobe,especiallyinthedevelopingcountry.6•TustartedhermalariaresearchinChinawhentheCulturalRevolutionwasinprogress.Inearly1969,Tuwasappointedastheheadoftheproject,namedProject523researchgroupatherinstitute.Sheandhercolleaguesexperimentedwith380extractsin2,000candidaterecipesbeforetheyfinallysucceeded.7•In1971,TuwasinspiredbymanyancientclassicworksonTCM.•Usingapioneeringlow-temperaturemethod,Tuandherteamfirstextractedartemisininfromasweetwormwoodplant(青蒿).8•Forthesakeofdrugsafety,shehadpersonallytakingtests,whichledtoherliverpoisoning,butshestillkeptonworking,regardlessofpickingsamplesinthewild,orintheindoorexperimentstudy.9Inspiration•AchievingmodernizationofTCMthroughscienceandtechnology.Tu‘ssuccessshowsthatTCMhastoembracemoderntechnologiesandlaboratorytoolsand,moreimportant,sticktotheessenceofthetime-honoredmedicalscience,practicinginnovationwhenusingTCMtheories.Tu'sNobelPrizewillpromptmorebasicscientificresearchintoancientTCMtextsandwaystoexploreresearchfindings.10•EffectivecombinationofTCMandWM.ThereareenormoustreasureinTCM,soitcanplayamoreimportantroleinmodernmedicine.Inaddition,asimpleapplicationofWesternmedicalstandardstoTCMwon'twork,ChinesemedicinedevelopmentneedsmoreopeninclusiveofChineseandWesterntomakebreakthroughs.11•Improvingtheinnovationmechanism.Chinashouldfocusoncultivatinggoodacademicresearchenvironmentandscientificresearchmechanismtoencouragemorescientists.Chinaspendsmorethan1billionyuan($156million)annuallyonTCM-relatedresearch,andthatinvestmentshouldbefurtherstrengthened.12Thankyou13