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3(200052),,,:20032022233:jianpingxie@yahoo.com,jianpingxie@vip.sina.comWTO,,1,,,,,,,,,()2:,,211:1),2),,3),,,,,,,,,,,,,,,,,(reverseengineering)233JOURNALOFCHINESEBIOTECHNOLOGY20033:1,;2;3,212,,,:(coretechnology)(platformtechnology);;,(degenerategene),,,(platforminventions),,,,,,,:1),;2),:,,,;,,,,,,,,,,,,(34)18(window)18,213[1](defensivepublishing)IBM,1996200110000IBM(IBMtechnicaldisclosurebulletin,)(priorart)IBMIBM,,,IBM,IBMNatureBiotech193:[2],,,(,263),,,,,,,,3[3]:,,,,,FDA,,,;;,,6:??,,:?,?,,,:?,,,,:?90,,,:?,,:?,500015000,,:,,,,,4[1],,,,,,,,,,2923(conceptualinvention)(unpredictable),,,,,,,,,,,,,,,,,,,,(WorldIntellectualPropertyOrganization,WIPO)EmsworthDesignInc.19601998,IBMTechnicalDisclosureBulletin,1998,IBM100,400IP.com,;,IP.com,,,,,,,,,,,[1]BarrettB.Defensiveuseofpublicationsinanintellectualpropertystrategy.NatBiotechnol.2002,20:191[2]AskenaziM,DriggersEM,HoltzmanDA,etal.Integretingtranscriptionalandmetaboliteprofilestodirecttheengineeringoflovastatin2producingfungalstrains.NatureBiotech,2003,21:150156[3]DaizadehH,MillerD,GlowallaA,etal.Ageneralapproachfordeterminingwhentopatent,publish,orprotectinformationasatradesecret.2002,20(10):10531054DecisionandImplementationofProperIntellectualPropertyProtectionforBiopharmaceuticalsCompanyXieJianping(SectionofIntellectualProperty,HengtaiLawFirmShanghai200052)AbstractIntellectualpropertyisthecornerstoneforobtainingcompetitiveadvantageinbiotechnologyandbiopharmaceuticalscompanies,amongwhichthepatentisoffirstimportance.Thedecisionoftheintellectualpropertyprotectionmustbaseonthelong2termstrategicgoals,thecost-benefitruleandinapragmaticway.Thepaperelucidatesthedecisionprocedureforthetradesecrets,patentanddefensivepublicationanditsimplementation.Examplesofplatformtechnology,drugsandbioinformaticssoftwarearealsopresented.KeywordsIntellectualpropertyBiopharmaceuticals393: