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83200270TheRequirementforFacilitiestoDetectandTreatmentofTumorsinSub-regionBAOShanglianZHOUYin,LAISongThispaperdescribesrequirementforthefacilitiesusedindetectionandtreatmentofthetumorsfortheinformationaboutsub-region.Thedefinitionofthetumorsub-regionwasgivenandprimaryresultswereintroduced.ThespecificationsneededtodevelopthesetechnologiestomeettherequirementaresatisfiedinChinaatpresentcondition.ButthereformforhospitalstomeetthecombinationbetweenphysiciansandphysicistsinradiologicaldepartmentandRadiotherapeuticaldepartmentareinurgent.KeyWords:Tumorsub-region,Tumordiagnosisandtreatmentfacility,Technicalrequirement200160551CTCTCTMRISPECT1PETPETCTMRI13011002101750048320027110(m)()PET(fMRI)[1]1PET[2]Ga-68EDTAPETFCV(1)[2]1.bpbCKCKdtdC21−=(1)CppCbK1k2BBB83200272ppbPETCVCC+=(2)(1)(2)CbCpCPETPETK1(ml/min/g)K2(1/min)DV=k1/K2Vp(ml/g)(1)(2)k1K2∫∫−+=dsCKdsCVKKCpppPET221)(VPCp(3)ppPETppPETCKVCKdsCVDVdsC)/()/1()(22+−+=∫∫(4)(LPISC)3FFF=(((n-2)n/(2(n2-1)))D2D2=(x-µ)’S-1(x-µ),nµS(K1,DV)α0.2,0.05,0.001FF0.20F0.2≤FF0.05,1F0.05≤FF0.012F0.01≤F3MRIK1DVFLevls2.Ga-68EDTAPETMRIk1DVF83200273Ga-68EDTAPETPETCTIEXACT/HRPETMRIDV,K1,F(2)K1,DV,F(S)(3)PET3.DVDVS2BOLDAN3CA(3X106)(46)42474T2(TE=18,37,56,and74ms;TR=1300ms).T2*24FLASH(TE=16,33,50,and67ms)TR=700ms(FOV=100-120mm,imagingmatrix256x256)0.5mm25-8T2WIandT2*WIR2*R2R2′=R2*-R2420.0E+002.0E-044.0E-046.0E-048.0E-041.0E-031.2E-030102030405060Time(min)Radioactivity83200274MRI[hematoxylinandeosin(H&E)]H&ET2WIandT2*WIR2(4)R24.(100µm)