靶点基因检测-妇科肿瘤-华大基因

FDAT-DM1TrastuzumabHER21/2/3HER2IHC1/2/3BevacizumabVEGFR1IHC1/2/3VEGFR2IHC1/2/3VEGFR3IHC1/2/3LapatinibHER21/2/3HER2IHC1/2/3PertuzumabHER21/2/3HER2IHC1/2/3EverolimusTemsirolimusHER2IHC1/2/3ERIHC1/2/3K-rascode12,13()1/2/3K-ras(FQ-PCR)FQ-PCR1/2/3PTENIHC1/2/3PIK3CAExon9,201/2/3ExemestaneERIHC1/2/3PRIHC1/2/3FulvestrantERIHC1/2/3PRIHC1/2/3TamoxifenCYP2D6(CYP2D6*1,*10)4ERIHC1/2/3PRIHC1/2/3ToremifeneERIHC1/2/3PRIHC1/2/3AnastrozoleLetrozoleCYP19A1(rs4646)4ERIHC1/2/3PRIHC1/2/3PlatinumERCC1IHC1/2/3ERCC1(C118T)4ERCC2(Lys751Gln)4TPMT(TPMT*1,*2,*3A,*3B,*3C)4XRCC1(Arg399Gln)4GSTP1(Ile105Val)4GSTT14GSTM14TaxinolDocetaxelVincaleukoblastinum-tubulinIIIIHC1/2/3ABCB1(MDR1)(2677GT/A)4CYP1B1(Leu432Val)4STMN1IHC1/2/3FluorouracilCapecitabineTYMS(TS)IHC1/2/3DPYD(DPD)(IVS14+1GA,1679TG,2846AT)4MTHFR(C677T)4TYMS(TS)(TYMSTSER*2,*3)4GemcitabineRRM1IHC1/2/3CDA(A79C)4DoxorubicinEpirubicinTOPOIIIHC1/2/3GSTP1(Ile105Val)4CyclophosphamideCYP2C9(CYP2C9*1,*2,*3)4CYP2C19(CYP2C19*1,*2,*3)4AbraxaneSPARCIHC1/2/3MethopterinMTHFR(C677T)4BevacizumabVEGFR1IHC1/2/3VEGFR2IHC1/2/3VEGFR3IHC1/2/3PazopanibVEGFR1IHC1/2/3VEGFR2IHC1/2/3VEGFR3IHC1/2/3TamoxifenCYP2D6(CYP2D6*1,*10)4ERIHC1/2/3PRIHC1/2/3CYP19A1(rs4646)4LetrozoleAnastrozoleERIHC1/2/3PRIHC1/2/3PlatinumERCC1IHC1/2/3ERCC1(C118T)4ERCC2(Lys751Gln)4TPMT(TPMT*1,*2,*3A,*3B,*3C)4XRCC1(Arg399Gln)4GSTP1(Ile105Val)4GSTT14GSTM14TaxinolDocetaxelVincaleukoblastinum-tubulinIIIIHC1/2/3ABCB1(MDR1)(2677GT/A)4CYP1B1(Leu432Val)4STMN1IHC1/2/3GemcitabineRRM1IHC1/2/3CDA(A79C)4EtoposideTOPOIIIHC1/2/3GSTP1(Ile105Val)4PemetrexedTYMS(TS)IHC1/2/3TYMS(TS)(TYMSTSER*2,*3)4TopotecanTOPOIIHC1/2/3IrinotecanUGT1A1(UGT1A1*1,*28,*6)4TOPOIIHC1/2/3CyclophosphamideIfosfamideCYP2C9(CYP2C9*1,*2,*3)4CYP2C19(CYP2C19*1,*2,*3)4DoxorubicinTOPOIIIHC1/2/3GSTP1(Ile105Val)4AbraxaneSPARCIHC1/2/3BevacizumabVEGFR1IHC1/2/3VEGFR2IHC1/2/3VEGFR3IHC1/2/3PlatinumERCC1IHC1/2/3ERCC1(C118T)4ERCC2(Lys751Gln)4TPMT(TPMT*1,*2,*3A,*3B,*3C)4XRCC1(Arg399Gln)4GSTP1(Ile105Val)4GSTT14GSTM14TaxinolDocetaxelVincaleukoblastinum-tubulinIIIIHC1/2/3ABCB1(MDR1)(2677GT/A)4CYP1B1(Leu432Val)4STMN1IHC1/2/3GemcitabineRRM1IHC1/2/3CDA(A79C)4PemetrexedTYMS(TS)IHC1/2/3TYMS(TS)(TYMSTSER*2,*3)4FluorouracilCapecitabineTYMS(TS)IHC1/2/3DPYD(DPD)(IVS14+1GA,1679TG,2846AT)4MTHFR(C677T)4TYMS(TS)(TYMSTSER*2,*3)4MitomycinNQO1(C609T)4IfosfamideCYP2C9(CYP2C9*1,*2,*3)4CYP2C19(CYP2C19*1,*2,*3)4TopotecanTOPOIIHC1/2/3IrinotecanUGT1A1(UGT1A1*1,*28,*6)4TOPOIIHC1/2/31234