肿瘤个性化用药基因检测

202532200502/399.9%0.1%DNASangerIlluminaHiseqCompleteGenomicsDNA1sangerSangerATCGPAGEDNADNA(dNTP)(ddNTP)ddNTP3-OHGATCdNTPsddNTPsX-Sanger800-1KbpTaqmanTaqmanSNPFamHexVicPCRSNP252NGSilluminaHiseq2000500Gb100bp14LifetechnologyIonProton3/PacificBiosciencePCRDNAdNTPDNA41DNADNA2MLPA(,multiplexligation-dependentprobeamplification),FISH(fluorescenceinsituhybridization)DigitalPCR(PCR)3SNPSNPSNPTaqmanPCRSNPlex48SNPsABISNaPshot1030SNP,SNPstream4DNAIllumina,IonTorrent,PacificBioScience,Nanopore454SOLiD201030100%7650%14012,3456DNADNAKRASEGFR11234567823GMP20076AB20