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FISHFISH1974Evans2070FISH1981HarperDNAG2090FISH1FISH(fluorescenceinsituhybridization):DNADNA--DNADNAFISH2FISH3FISHFISH:1234FISH1kbDNA5FISH6DNA100%cDNA4FISHFISHFISH1980BaumanRNA-3DNA--1980DNAmRNADNA1FISHFISHFISHFISHFISHmRNAsDNAFISHComparativegenomichybridization200FISHFISHmRNAFISHFISH2090FISHFISH12FISHmRNAsFISH2FISH[1]Pinkel1986mRNAFISHFISHDNADNAFISHX1~2mmX15mmRNAsFISHmRNAGreenfluorescenceprotein,GFPGFPFISHFISHFISHFISH