1CA100mgBC65DARB2CABCD3NYHABABCD4CABCD5BABCD6DABCD7ACEI/ARBCABCD8AABCD9ACEIBABCD10AA70B75C78D801DA.AB.CC.DD.E2AA.B.C.D.3CA43B53C63D734BA.B.C.D.5AA.40mg/dB.20mg/dC.20mg/dD.80mg/d6BA.CYP1A2B.CYP3A4C.CYP2C9D.CYP2D67DA.B.C.D.8AA.B.C.D.9(2016):ASTALT3CA.40UB.80UC.120UD.160U10DA.2B.3C.5D.10IBD1DAUCBCDCIBDDUC110mg/d12DANUDT15TPMTIBDAZAB6-MP6-MPAZA6-MPCMTXDCYP3A4P-EIBD3AABCIBDDIBDEIBD4CAUCCDCDBSASP530C5-ASADIBD5AABUCCDCUCCDD/EIBD6DA519BCCCFCChina(Colitis)(Crohn'sdisease)CIBDStep-upTop-downD7DABCDIBD8DAIBDBIBDCIBDIBDDIBD9DA5-ASAUCBCDAZACCDDE79%10DA5-ASAUCB5-ASA35CSASPDSASP1.DA.B.C.D.2AABCD3AABCD4BA3B5C7D95CA6B8C10D126CABC7CA3-6B6-12C6-18D18-248CABCD9(Chickenpox)-DABCD10DABCDCOPD1COPDBDEABCDE2AA.B.3AA.B.4AA.B.5COPDACDABCD6ABCDABCD775AA.B.8ACABCDE92013COPDABCDAmMRCCATBCD10AA.B.1100%AABCD2CABCD3CKD1-4BA0.5B0.8C1D1.54BABCD5CAgBmgC%Dm6GFR55ml/minCA1B2C3D47fe=AA0.5B1C1.5D28CABCD9AABCD10AARAASBCDCCB1CollaborativeDrugTherapyManagement,CDTMCA1972B1987C1997D19882ABCDA.B.C.D.3BDEABCDE4BA.B.C.D.5ABCDABCD6ABCEABCDE7ABCDA.B.C./D.8RxcaresRBA.B.C.D.9ABCDEABCDE10500mlA2B3C4D5MTM1DA.B.C.D.2DA.B.point-and-spellboardC.D.3MRPBABCD4BABCD5DABCINRD6MTMDAMTRBPMRCMAPD7DA.B.C.D.8MAPBABCD98940kg108umol/LCockcroft-GaultA20.1ml/minB19.7ml/minC18.6ml/minD21.3ml/min10MTMABCMTMDMTM1BABCD2WHOBA8%B10%C15%D20%3NE5-HT(NaSSA)CABCD4CABCD5AABCD6BABCD7MAOIBABCD8BABCD9DABCD10HAM-DCABCD15.AABCDE21.BABCDE39AA.B.C.D.E.410AA.B.C.D.E.57BA.B.C.D.E.64.CABCDE76.DABCDE82.DABCDE93.BABCDE108DA.B.C.D.E.12.5212012090/60mmHgCA.B.C.D.E.210CA25~50mg/dB25~70mg/dC75~100mg/dD75~150mg/dE75~175mg/d39EABCDE43.482V1V5ST0.3mmTDA.B.C.D.E.51.DABCDE67DABCDE75.FA.B.C.D.E.F86WHOFABCDEF94.DA.B.C.D.E.1081CABCD1BABCD2ACR/EULAR2009106EABCDE3CA.B.C.D.E.4CA7mg/dl3mg/dlB3mg/dl7mg/dlC7mg/dl6mg/dlD7mg/dl9mg/dlE9mg/dl7mg/dl5AA.B.C.D.E.6FABCDEF7BA.B.C.D.E.8DA.B.C.D.E.9CABCD10AA.B.C.D.E.1CA.100B.200C.300D.4002g/dDA.50B.40C.30D.203AA.B.C.D.4CA.0.5gB.1gC.2gD.3g5BA.3B.4C.5D.66WHOCA.3B.4C.5D.67DA.10%-15%B.20%-30%C.30%-50%D.55%-65%8AA.4kcal/gB.7kcal/gC.9kcal/gD.11kcal/g9DA.B.C.D.10DA.25B.30C.35D.4012ABAB100mg/dC110mgBidD2BA.B.C.D.3ABCDA.B.C.D.4ABCDA.()B.()24h()C.D.CT/MRI5ABCDA.B.C.D.&6CA1~6B6~24C24~48D3~3721CTECGDABCD8AA.B.C.D.972Bp140/90mmHgCTCABCD10ABCA.B.C.D.1CABCD2ABCDABCD3ABCDABCD4CABCD5ABCDABCD6ABCDEABbCDEII7DAbBCCBCARBDACEIE8AABCD9ABCDABCD10AA,,BCD1ABA.B..D.2DAB.C.D.3ABCD.B.C.C.4ACDAB...5BAB..D.6BAB.C.D.7CAB.C.D.8BCA.B.C.D.9ABCDA.C.D.10CAB.C.D.1DABCD2CABCD3BABCD4AABCD5ClockCKIBA1994B1984C2004D20146BAClockBPerCDBTDTim7AABCD8???CA2014B2015C2017D20189CABC;D10CABCD120163ABCDEFABCDEF2DABCD3CABCD42020DA3B4C5D65AABCD6BABCD7DABCD8AABCD9DABBD10BABCD