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LOGOSomehumanGPCRsinvolvedinagingandcertainage-relatedpathologies(theVFTmodule)allostericsite(theheptahelicaldomain)SuchcompoundsmightsoonprovetobeexcellentdrugstotreatvariousdiseasesincludinganxietyParkinson’sdiseasedepressiondrugaddictionschizophrenia(精神分裂症)osteoporosis(骨质疏松症)newtasteenhancersLOGOLOGOpharmacologicalbridgeTextLimitationsoftheapproach21234LOGOContentsNoconsensushasbeenreached1Thepatientshavenorespond2Drugsmaybeindirecttopathogenesis3Drug’sactionisunexpectedtoitsfeature4LOGOContentsNoconsensushasbeenreached1Thepatientshavenorespond2Drugsmaybeindirecttopathogenesis3Drug’sactionisunexpectedtoitsfeature4LOGOContentsNoconsensushasbeenreached1Thepatientshavenorespond2Drugsmaybeindirecttopathogenesis3Drug’sactionisunexpectedtoitsfeature4LOGOContentsNoconsensushasbeenreached1Thepatientshavenorespond2Drugsmaybeindirecttopathogenesis3Drug’sactionisunexpectedtoitsfeature4biologicaltreatmentmonitoringmulti-markerlargescaleautomatedmeasuresbiologicaldifferentialdiagnosticsystemPerspectiveItistobehopedthatanadmixtureofnewtechniquesandstrategiesofgenomics,proteomics,whichenabletoworktogetherwiththe‘‘old’’biochemicalapproaches.LOGOLOGOMadebyjason_wjbLunchtime!!!anddon’tforgettheimportanceofGPCRs